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The nature and identification of quantitative trait loci: A community's view

Abiola, O and Angel, JM and Avner, P and Bachmanov, AA and Belknap, JK and Bennett, B and Blankenhorn, EP and Blizard, DA and Bolivar, V and Brockmann, GA and Buck, KJ and Bureau, JF and Casley, WL and Chesler, EJ and Cheverud, JM and Churchill, GA and Cook, M and Crabbe, JC and Crusio, WE and Darvasi, A and de Haan, G and Demant, P and Doerge, RW and Elliott, RW and Farber, CR and Flaherty, L and Flint, J and Gershenfeld, H and Gibson, JP and Gu, J and Gu, W and Himmelbauer, H and Hitzemann, R and Hsu, HC and Hunter, K and Iraqi, FA and Jansen, RC and Johnson, TE and Jones, BC and Kempermann, G and Lammert, F and Lu, L and Manly, KF and Matthews, DB and Medrano, JF and Mehrabian, M and Mittleman, G and Mock, BA and Mogil, JS and Montagutelli, X and Morahan, G and Mountz, JD and Nagase, H and Nowakowski, RS and O'Hara, BF and Osadchuk, AV and Paigen, B and Palmer, AA and Peirce, JL and Pomp, D and Rosemann, M and Rosen, GD and Schalkwyk, LC and Seltzer, Z and Settle, S and Shimomura, K and Shou, S and Sikela, JM and Siracusa, LD and Spearow, JL and Teuscher, C and Threadgill, DW and Toth, LA and Toye, AA and Vadasz, C and Van Zant, G and Wakeland, E and Williams, RW and Zhang, HG and Zou, F (2003) 'The nature and identification of quantitative trait loci: A community's view.' Nature Reviews Genetics, 4 (11). 911 - 916. ISSN 1471-0056

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Abstract

This white paper by eighty members of the Complex Trait Consortium presents a community's view on the approaches and statistical analyses that are needed for the identification of genetic loci that determine quantitative traits. Quantitative trait loci (QTLs) can be identified in several ways, but is there a definitive test of whether a candidate locus actually corresponds to a specific QTL?

Item Type: Article
Subjects: Q Science > QH Natural history > QH426 Genetics
Divisions: Faculty of Science and Health > Biological Sciences, School of
Depositing User: Jim Jamieson
Date Deposited: 24 Feb 2015 19:18
Last Modified: 17 Aug 2017 17:46
URI: http://repository.essex.ac.uk/id/eprint/10980

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