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New tools for the high throughput characterization of rat genomic DNA samples

Knoblauch, M and Gösele, C and Zimdahl, H and Hieke, B and Himmelbauer, H and Schalkwyk, L and Lindpaintner, K and Ganten, D and Lehrach, H (2000) 'New tools for the high throughput characterization of rat genomic DNA samples.' Journal of Experimental Animal Science, 41 (1-2). 35 - 37. ISSN 0939-8600

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Linkage studies and positional cloning projects for the identification of disease related genes require the genetic characterization of large numbers of genomic DNA samples. The application of spotting robots enables the production of high density filters representing several thousand DNA probes. To take full advantage of the potential of these filters we have established a new, hybridization based Interspersed Repetitive Sequence (IRS-)marker system for the rat genome. This marker panel was shown to be useful for rapid genotyping of many multigenic crosses as well as high throughput characterization of large insert genomic libraries.

Item Type: Article
Subjects: Q Science > QH Natural history > QH426 Genetics
Divisions: Faculty of Science and Health > Life Sciences, School of
Depositing User: Jim Jamieson
Date Deposited: 29 Jun 2017 20:21
Last Modified: 15 Oct 2019 10:15

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