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RNA regulatory networks in animals and plants: A long noncoding RNA perspective

Bai, Y and Dai, X and Harrison, AP and Chen, M (2015) 'RNA regulatory networks in animals and plants: A long noncoding RNA perspective.' Briefings in Functional Genomics, 14 (2). 91 - 101. ISSN 2041-2649

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A recent highlight of genomics research has been the discovery of many families of transcripts which have function but do not code for proteins. An important group is long noncoding RNAs (lncRNAs), which are typically longer than 200 nt, and whose members originate from thousands of loci across genomes. We review progress in understanding the biogenesis and regulatory mechanisms of lncRNAs. We describe diverse computational and high throughput technologies for identifying and studying lncRNAs. We discuss the current knowledge of functional elements embedded in lncRNAs as well as insights into the lncRNA-based regulatory network in animals. We also describe genome-wide studies of large amount of lncRNAs in plants, as well as knowledge of selected plant lncRNAs with a focus on biotic/abiotic stress-responsive lncRNAs.

Item Type: Article
Subjects: Q Science > QH Natural history > QH301 Biology
Divisions: Faculty of Science and Health > Mathematical Sciences, Department of
Depositing User: Jim Jamieson
Date Deposited: 04 Mar 2015 12:00
Last Modified: 30 Mar 2021 23:15

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