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Job Strain and the Risk of Stroke

Fransson, EI and Nyberg, ST and Heikkil�, K and Alfredsson, L and Bjorner, JB and Borritz, M and Burr, H and Dragano, N and Geuskens, GA and Goldberg, M and Hamer, M and Hooftman, WE and Houtman, IL and Joensuu, M and Jokela, M and Knutsson, A and Koskenvuo, M and Koskinen, A and Kumari, M and Leineweber, C and Lunau, T and Madsen, IEH and Hanson, LLM and Nielsen, ML and Nordin, M and Oksanen, T and Pentti, J and Pejtersen, JH and Rugulies, R and Salo, P and Shipley, MJ and Steptoe, A and Suominen, SB and Theorell, T and Toppinen-Tanner, S and Vahtera, J and Virtanen, M and V��n�nen, A and Westerholm, PJM and Westerlund, H and Zins, M and Britton, A and Brunner, EJ and Singh-Manoux, A and Batty, GD and Kivim�ki, M (2015) 'Job Strain and the Risk of Stroke.' Stroke, 46 (2). pp. 557-559. ISSN 0039-2499

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Abstract

Background and Purpose?Psychosocial stress at work has been proposed to be a risk factor for cardiovascular disease. However, its role as a risk factor for stroke is uncertain. Methods?We conducted an individual-participant-data meta-analysis of 196 380 males and females from 14 European cohort studies to investigate the association between job strain, a measure of work-related stress, and incident stroke. Results?In 1.8 million person-years at risk (mean follow-up 9.2 years), 2023 first-time stroke events were recorded. The age- and sex-adjusted hazard ratio for job strain relative to no job strain was 1.24 (95% confidence interval, 1.05;1.47) for ischemic stroke, 1.01 (95% confidence interval, 0.75;1.36) for hemorrhagic stroke, and 1.09 (95% confidence interval, 0.94;1.26) for overall stroke. The association with ischemic stroke was robust to further adjustment for socioeconomic status. Conclusion?Job strain may be associated with an increased risk of ischemic stroke, but further research is needed to determine whether interventions targeting job strain would reduce stroke risk beyond existing preventive strategies.

Item Type: Article
Uncontrolled Keywords: psychological; stress; stroke; work
Subjects: H Social Sciences > H Social Sciences (General)
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Faculty of Social Sciences
Faculty of Social Sciences > Institute for Social and Economic Research
SWORD Depositor: Elements
Depositing User: Elements
Date Deposited: 25 Sep 2015 10:13
Last Modified: 06 Jan 2022 13:40
URI: http://repository.essex.ac.uk/id/eprint/15067

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