Research Repository

Design of robust metabolic pathways

Umeton, Renato and Stracquadanio, Giovanni and Sorathiya, Anilkumar and Liò, Pietro and Papini, Alessio and Nicosia, Giuseppe (2011) Design of robust metabolic pathways. In: the 48th Design Automation Conference, 2011-06-05 - 2011-06-10.

Full text not available from this repository.

Abstract

In this paper we investigate plant photosynthesis and microbial fuel cells. We report the following: 1) we introduce and validate a novel multi-objective optimization algorithm, PMO2; 2) in photosynthesis we increase the yield of 135%, while in Geobacter sulfurreducens we determine the tradeoff for growth versus redox properties; 3) finally, we discuss Pareto-Front as an estimator of robust metabolic pathways. © 2011 ACM.

Item Type: Conference or Workshop Item (Paper)
Additional Information: Published proceedings: Proceedings - Design Automation Conference
Uncontrolled Keywords: Metabolic engineering; Mutational Robustness; Geobacter sulfurreducens; Carbon metabolism; Multi-objective Optimization
Subjects: Q Science > QA Mathematics > QA75 Electronic computers. Computer science
Divisions: Faculty of Science and Health
Faculty of Science and Health > Computer Science and Electronic Engineering, School of
SWORD Depositor: Elements
Depositing User: Elements
Date Deposited: 13 Feb 2017 13:33
Last Modified: 15 Jan 2022 00:39
URI: http://repository.essex.ac.uk/id/eprint/18707

Actions (login required)

View Item View Item