Umeton, Renato and Stracquadanio, Giovanni and Sorathiya, Anilkumar and Liò, Pietro and Papini, Alessio and Nicosia, Giuseppe (2011) Design of robust metabolic pathways. In: the 48th Design Automation Conference, 2011-06-05 - 2011-06-10.
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Official URL: http://dl.acm.org/citation.cfm?id=2024724
Abstract
In this paper we investigate plant photosynthesis and microbial fuel cells. We report the following: 1) we introduce and validate a novel multi-objective optimization algorithm, PMO2; 2) in photosynthesis we increase the yield of 135%, while in Geobacter sulfurreducens we determine the tradeoff for growth versus redox properties; 3) finally, we discuss Pareto-Front as an estimator of robust metabolic pathways. © 2011 ACM.
Item Type: | Conference or Workshop Item (Paper) |
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Additional Information: | Published proceedings: Proceedings - Design Automation Conference |
Uncontrolled Keywords: | Metabolic engineering; Mutational Robustness; Geobacter sulfurreducens; Carbon metabolism; Multi-objective Optimization |
Subjects: | Q Science > QA Mathematics > QA75 Electronic computers. Computer science |
Divisions: | Faculty of Science and Health Faculty of Science and Health > Computer Science and Electronic Engineering, School of |
SWORD Depositor: | Elements |
Depositing User: | Elements |
Date Deposited: | 13 Feb 2017 13:33 |
Last Modified: | 15 Jan 2022 00:39 |
URI: | http://repository.essex.ac.uk/id/eprint/18707 |
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