Mills, MC and Barban, N and Tropf, FC (2018) 'The Sociogenomics of Polygenic Scores of Reproductive Behavior and Their Relationship to Other Fertility Traits.' The Russell Sage Foundation Journal of the Social Sciences, 4 (4). pp. 122-136. ISSN 2377-8253
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Abstract
Human reproductive behavior until relatively recently has been explained exclusively via individual and social characteristics. This article applies results from a recent Genome-Wide Association Study that combined sixty-two data sources to isolate twelve genetic loci associated with reproductive behavior. We create polygenic scores that allow us to include a summary variable of genetic factors into our statistical models. We use four datasets: the U.S. Health and Retirement Study, Dutch LifeLines, TwinsUK and the Swedish Twin register. First, we provide a brief overview of the dominant explanations of reproductive behavior. Second, we test the predictive power of polygenic scores. Third, we interrogate the robustness of our models using a series of sensitivity analyses to take into account possible confounders due to population stratification and selection.
| Item Type: | Article |
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| Uncontrolled Keywords: | human reproduction, polygenic scores, genetics, educational attainment, age at first birth, number of children ever born, fertility |
| Subjects: | H Social Sciences > HM Sociology |
| Divisions: | Faculty of Social Sciences Faculty of Social Sciences > Institute for Social and Economic Research |
| SWORD Depositor: | Elements |
| Depositing User: | Elements |
| Date Deposited: | 06 Sep 2018 08:59 |
| Last Modified: | 06 Jan 2022 13:45 |
| URI: | http://repository.essex.ac.uk/id/eprint/22118 |
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