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An interoceptive model of bulimia nervosa: A neurobiological systematic review

Klabunde, Megan and Collado, Danielle and Bohon, Cara (2017) 'An interoceptive model of bulimia nervosa: A neurobiological systematic review.' Journal of Psychiatric Research, 94. 36 - 46. ISSN 0022-3956

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Abstract

The objective of our study was to examine the neurobiological support for an interoceptive sensory processing model of bulimia nervosa (BN). To do so, we conducted a systematic review of interoceptive sensory processing in BN, using the PRISMA guidelines. We searched PsychInfo, Pubmed, and Web of Knowledge databases to identify biological and behavioral studies that examine interoceptive detection in BN. After screening 390 articles for inclusion and conducting a quality assessment of articles that met inclusion criteria, we reviewed 41 articles. We found that global interoceptive sensory processing deficits may be present in BN. Specifically there is evidence of abnormal brain function, structure and connectivity in the interoceptive neural network, in addition to gastric and pain processing disturbances. These results suggest that there may be a neurobiological basis for global interoceptive sensory processing deficits in BN that remain after recovery. Data from taste and heart beat detection studies were inconclusive; some studies suggest interoceptive disturbances in these sensory domains. Discrepancies in findings appear to be due to methodological differences. In conclusion, interoceptive sensory processing deficits may directly contribute to and explain a variety of symptoms present in those with BN. Further examination of interoceptive sensory processing deficits could inform the development of treatments for those with BN.

Item Type: Article
Uncontrolled Keywords: Interoception, Bulimia nervosa, Pain, Gastric distention, Taste, Heartbeat
Subjects: R Medicine > RA Public aspects of medicine > RA790 Mental Health
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Faculty of Science and Health > Psychology, Department of
Depositing User: Elements
Date Deposited: 10 Jun 2019 10:29
Last Modified: 10 Jun 2019 11:15
URI: http://repository.essex.ac.uk/id/eprint/24781

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