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Homocysteine and risk of open-angle glaucoma

Bleich, S and Jünemann, A and von Ahsen, N and Lausen, B and Ritter, K and Beck, G and Naumann, GOH and Kornhuber, J (2002) 'Homocysteine and risk of open-angle glaucoma.' Journal of Neural Transmission, 109 (12). pp. 1499-1504. ISSN 0300-9564

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Homocysteine levels and the frequency of heterozygous methylenetetrahydrofolate reductase (MTHFR) C677T mutation are increased in open-angle glaucoma. Since homocysteine can induce vascular injury, alterations in extracellular matrix remodelling, and neuronal cell death, these findings may have important implications for understanding glaucomatous optic neuropathy.

Item Type: Article
Uncontrolled Keywords: Glaucoma; homocysteine; MTHFR polymorphism; glaucomatous optic neuropathy
Subjects: R Medicine > RE Ophthalmology
Divisions: Faculty of Science and Health
Faculty of Science and Health > Mathematical Sciences, Department of
SWORD Depositor: Elements
Depositing User: Elements
Date Deposited: 04 Jul 2012 20:47
Last Modified: 06 Jan 2022 13:24

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