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Differential weight restoration on olanzapine versus fluoxetine in identical twins with anorexia nervosa

Duvvuri, Vikas and Cromley, Taya and Klabunde, Megan and Boutelle, Kerri and Kaye, Walter H (2012) 'Differential weight restoration on olanzapine versus fluoxetine in identical twins with anorexia nervosa.' International Journal of Eating Disorders, 45 (2). 294 - 297. ISSN 0276-3478

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Abstract

Objective: No studies have compared the response to selective serotonin reuptake inhibitors and atypical antipsychotics in anorexia nervosa. This case study examines such a comparison. Method: This report describes a case of 12-year-old identical twins with anorexia nervosa, one of whom was treated with olanzapine and the other with fluoxetine, while undergoing family therapy. Results: Twin A treated with fluoxetine went from 75 to 84.4% ideal body weight, while Twin B treated with olanzapine went from 72 to 99.9% ideal body weight over the course of 9 months. Discussion: This case supports the need for adequately powered, controlled clinical trials to test the efficacy of olanzapine in adolescents presenting with anorexia nervosa. © 2011 by Wiley Periodicals, Inc.

Item Type: Article
Divisions: Faculty of Science and Health > Psychology, Department of
Depositing User: Elements
Date Deposited: 15 Nov 2019 10:18
Last Modified: 15 Nov 2019 10:18
URI: http://repository.essex.ac.uk/id/eprint/25537

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