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Variation on the serotonin transporter gene and bias in the interpretation of ambiguity

Fox, Elaine and Standage, Helen (2012) 'Variation on the serotonin transporter gene and bias in the interpretation of ambiguity.' Journal of Cognitive Psychology, 24 (1). pp. 106-114. ISSN 2044-5911

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Abstract

Previous studies have established that carriers of the low expression form of the serotonin transporter gene have an early attentional bias towards threatening relative to benign or positive information, in contrast to those with a high expression form of this gene. In the present study we extend this finding of a link between variation on the serotonin transporter gene and attentional bias to biases in the interpretation of emotional ambiguity. Specifically, a series of homophones were verbally presented (e.g., PAIN/PANE) and in line with research on attentional bias, participants with a low expression form of the serotonin transporter were more likely to select the threatening meaning more than those with a high expression form of the gene. This is the first evidence that variation on the serotonin transporter gene is correlated with interpretative bias and further strengthens the proposal that genetic variation, like processing bias, may play a role in the development and maintenance of emotional disorders.

Item Type: Article
Uncontrolled Keywords: Cognitive bias; Interpretation bias; Serotonin transporter gene
Subjects: B Philosophy. Psychology. Religion > BF Psychology
Divisions: Faculty of Science and Health > Psychology, Department of
Depositing User: Jim Jamieson
Date Deposited: 05 Jul 2012 15:45
Last Modified: 05 Jul 2012 15:45
URI: http://repository.essex.ac.uk/id/eprint/2795

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