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Effects of rTMS on an Auditory Oddball Task: A Pilot Study of Cortical Plasticity and the EEG

Cooper, NR and Fitzgerald, PB and Croft, RJ and Upton, DJ and Segrave, RA and Daskalakis, ZJ and Kulkarni, J (2008) 'Effects of rTMS on an Auditory Oddball Task: A Pilot Study of Cortical Plasticity and the EEG.' Clinical EEG and Neuroscience, 39 (3). pp. 139-143. ISSN 1550-0594

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<jats:p> The objective of this study was to explore the effects of 1Hz repetitive transcranial magnetic stimulation (rTMS) applied to dorsal lateral prefrontal cortex (DLPFC) on both an EEG index of cortical excitation and inhibition, event-related desynchronization/synchronization (ERD/S) and on the P300 component of an auditory oddball-induced ERP. Eight normal participants received 15 minutes of 1Hz rTMS at 110% of the resting motor threshold to right DLPFC. ERD/S of alpha and beta bands was measured during an auditory oddball task immediately before and after stimulation. </jats:p><jats:p> There was significantly less alpha desynchronization post-TMS, and this effect was widespread excepting posterior midline sites. No changes were found to oddball-P300 amplitudes or latencies. In conclusion, the findings of less alpha desynchronization post-TMS are compatible with notions of slow rTMS causing a decrease in cortical excitation. </jats:p>

Item Type: Article
Uncontrolled Keywords: depression; electroencephaolgraphy; P300; transcranial magnetic stimulation
Subjects: B Philosophy. Psychology. Religion > BF Psychology
Divisions: Faculty of Science and Health
Faculty of Science and Health > Psychology, Department of
SWORD Depositor: Elements
Depositing User: Elements
Date Deposited: 06 Jul 2012 12:32
Last Modified: 15 Jan 2022 00:58

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