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Life-Course Partnership Status and Biomarkers in Midlife: Evidence From the 1958 British Birth Cohort.

Ploubidis, George B and Silverwood, Richard J and DeStavola, Bianca and Grundy, Emily (2015) 'Life-Course Partnership Status and Biomarkers in Midlife: Evidence From the 1958 British Birth Cohort.' American Journal of Public Health, 105 (8). pp. 1596-1603. ISSN 0090-0036

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Objectives We examined the association between trajectories of partnership status over the life course and objectively measured health indicators in midlife. Methods We used data from 4 waves (1981, 1991, 2000, and 2002-2004) of the British National Child Development Study (NCDS), a prospective cohort study that includes all people born in Britain during 1 week in March 1958 (n = 18 558). Results After controlling for selection attributable to early-life and early-adulthood characteristics, we found that life-course trajectories of partnership status were associated with hemostatic and inflammatory markers, the prevalence of metabolic syndrome and respiratory function in midlife. Never marrying or cohabiting was negatively associated with health in midlife for both genders, but the effect was more pronounced in men. Women who had married in their late 20s or early 30s and remained married had the best health in midlife. Men and women in cohabiting unions had midlife health outcomes similar to those in formal marriages. Conclusions Partnership status over the life course has a cumulative effect on a wide range of objectively measured health indicators in midlife.

Item Type: Article
Uncontrolled Keywords: Humans; Tissue Plasminogen Activator; C-Reactive Protein; Fibrinogen; von Willebrand Factor; Fibrin Fibrinogen Degradation Products; Vital Capacity; Cohort Studies; Marital Status; Single Person; Age Factors; Sex Factors; Health Status; Adult; Middle Aged; Female; Male; Young Adult; Biomarkers; United Kingdom; Metabolic Syndrome
Divisions: Faculty of Social Sciences
Faculty of Social Sciences > Institute for Social and Economic Research
SWORD Depositor: Elements
Depositing User: Elements
Date Deposited: 04 Mar 2021 14:21
Last Modified: 18 Aug 2022 11:34

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