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The Role of Ribosomal Protein S6 Kinases in Plant Homeostasis

Obomighie, Irabonosi and Lapenas, Kestutis and Murphy, Billy E and Bowles, Alexander MC and Bechtold, Ulrike and Prischi, Filippo (2021) 'The Role of Ribosomal Protein S6 Kinases in Plant Homeostasis.' Frontiers in Molecular Biosciences, 8. ISSN 2296-889X

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The p70 ribosomal S6 kinase (S6K) family is a group of highly conserved kinases in eukaryotes that regulates cell growth, cell proliferation, and stress response via modulating protein synthesis and ribosomal biogenesis. S6Ks are downstream effectors of the Target of Rapamycin (TOR) pathway, which connects nutrient and energy signaling to growth and homeostasis, under normal and stress conditions. The plant S6K family includes two isoforms, S6K1 and S6K2, which, despite their high level of sequence similarity, have distinct functions and regulation mechanisms. Significant advances on the characterization of human S6Ks have occurred in the past few years, while studies on plant S6Ks are scarce. In this article, we review expression and activation of the two S6K isoforms in plants and we discuss their roles in mediating responses to stresses and developmental cues.

Item Type: Article
Uncontrolled Keywords: ribosomal protein S6 kinases, plant homeostasis, abiotic stress, cell signaling, stress response
Divisions: Faculty of Science and Health > Life Sciences, School of
Depositing User: Elements
Date Deposited: 12 Mar 2021 08:53
Last Modified: 12 Mar 2021 09:15

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