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Oxytocin administration versus emotion training in healthy males: Considerations for future research

Daughters, Katie and Rees, Aled and Hunnikin, Laura and Wells, Amy and Hall, Jeremy and van Goozen, Stephanie (2021) 'Oxytocin administration versus emotion training in healthy males: Considerations for future research.' Philosophical Transactions of the Royal Society B: Biological Sciences. ISSN 0962-8436 (In Press)

PTRS manuscript 4 - Daughters et al.pdf - Accepted Version

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Identifying emotions correctly is essential for successful social interaction. There is therefore a keen interest in designing therapeutic interventions to improve emotion recognition in individuals who struggle with social interaction. The neuropeptide oxytocin has been proposed as a potential physiological intervention due to its important role in emotion recognition and other aspects of social cognition. However, there are a number of caveats to consider with the current form of intranasal oxytocin commonly used in the literature. Psychological interventions, on the other hand, do not carry the same caveats, and there is therefore a need to understand how intranasal oxytocin administration compares to psychological interventions designed to target the same psychological phenomena; and whether a combined intervention approach may provide additive benefits. Here we present a pilot, proof of concept study in healthy volunteers comparing the effect of intranasal oxytocin against a validated emotion training program, finding that the psychological intervention, and not intranasal oxytocin, improved emotion recognition specifically for angry expressions. We discuss the theoretical implications of the research for future clinical trials.

Item Type: Article
Uncontrolled Keywords: oxytocin; emotion training; emotion recognition; empathy
Divisions: Faculty of Science and Health
Faculty of Science and Health > Psychology, Department of
SWORD Depositor: Elements
Depositing User: Elements
Date Deposited: 11 Nov 2021 11:53
Last Modified: 06 Jan 2022 14:33

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