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Does chromatin function as a metabolite reservoir?

Nirello, Vinícius D and Rodrigues de Paula, Dieggo and Araújo, Nathália VP and Varga-Weisz, Patrick D (2022) 'Does chromatin function as a metabolite reservoir?' Trends in Biochemical Sciences, 47 (9). pp. 732-735. ISSN 0167-7640

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Alternative histone acylations integrate gene expression with cellular metabolic states. Recent measurements of cellular acyl-coenzyme A (acyl-CoA) pools highlight the potential that histone post-translational modifications (PTMs) contribute directly to the regulation of metabolite pools. A metabolite-centric view throws new light onto roles and evolution of histone PTMs.

Item Type: Article
Uncontrolled Keywords: Chromatin; Acyl Coenzyme A; Histones; Protein Processing, Post-Translational; Acylation
Divisions: Faculty of Science and Health
Faculty of Science and Health > Life Sciences, School of
SWORD Depositor: Elements
Depositing User: Elements
Date Deposited: 25 May 2022 10:08
Last Modified: 13 Oct 2022 12:01

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