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Effects of assuming constant optical scattering on haemoglobin concentration measurements using NIRS during a Valsalva manoeuvre.

Gao, L and Elwellelwell, CE and Kohl-Bareis, M and Gramer, M and Cooper, CE and Leung, TS and Tachtsidis, I (2011) Effects of assuming constant optical scattering on haemoglobin concentration measurements using NIRS during a Valsalva manoeuvre. In: UNSPECIFIED, ? - ?.

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Abstract

Resolving for changes in concentration of tissue chromophores in the human adult brain with near-infrared spectroscopy has generally been based on the assumption that optical scattering and pathlength remain constant. We have used a novel hybrid optical spectrometer that combines multi-distance frequency and broadband systems to investigate the changes in scattering and pathlength during a Valsalva manoeuvre in 8 adult volunteers. Results show a significant increase in the reduced scattering coefficient of 17% at 790nm and 850nm in 4 volunteers during the peak of the Valsalva. However, these scattering changes do not appear to significantly affect the differential pathlength factor and the tissue haemoglobin concentration measurements.

Item Type: Conference or Workshop Item (UNSPECIFIED)
Additional Information: Published proceedings: Advances in experimental medicine and biology
Subjects: Q Science > QH Natural history > QH301 Biology
R Medicine > R Medicine (General)
Depositing User: Admin
Date Deposited: 04 Aug 2011 15:27
Last Modified: 17 Aug 2017 18:18
URI: http://repository.essex.ac.uk/id/eprint/373

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