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Key Cellular Components and Interactive Histocompatibility Molecules Regulating Tolerance to the Fetal Allograft

Spencer, PS and Hakam, SM and Laissue, PP and Jabeen, A and Jain, P and Hayrabedyan, S and Todorova, K and Blanch, A and Mcelhinney, JMWR and Muhandiram, N and Alkhatib, S and Dealtry, GB and Miranda-Sayago, JM and Fernández, N (2012) 'Key Cellular Components and Interactive Histocompatibility Molecules Regulating Tolerance to the Fetal Allograft.' American Journal of Reproductive Immunology, 68 (2). 95 - 99. ISSN 1046-7408

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Abstract

Implantation is a major landmark in life. It involves the correct apposition of the embryo in the maternal endometrium. The cellular environment influences placenta development, and direct contact of the fetus with maternal tissues is achieved through decidual cells. At the decidua, and at systemic level, the correct balance of cells potentially acting as antigen-presenting cells and histocompatibility products play a pivotal role in achieving feto-maternal tolerance. Here, we review some of the current issues associated with the interplay between cells and molecules needed for pregnancy development. © 2012 John Wiley & Sons A/S.

Item Type: Article
Subjects: Q Science > QH Natural history > QH301 Biology
Divisions: Faculty of Science and Health > Life Sciences, School of
Depositing User: Jim Jamieson
Date Deposited: 22 Jan 2013 11:25
Last Modified: 07 Sep 2019 00:15
URI: http://repository.essex.ac.uk/id/eprint/5190

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