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Preperceptual and Stimulus-Selective Enhancement of Low-Level Human Visual Cortex Excitability by Sounds

Romei, Vincenzo and Murray, Micah M and Cappe, Céline and Thut, Gregor (2009) 'Preperceptual and Stimulus-Selective Enhancement of Low-Level Human Visual Cortex Excitability by Sounds.' Current Biology, 19 (21). pp. 1799-1805. ISSN 0960-9822

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Evidence of multisensory interactions within low-level cortices and at early post-stimulus latencies [1-6] has prompted a paradigm shift in conceptualizations of sensory organization [7-10]. However, the mechanisms of these interactions and their link to behavior remain largely unknown. One behaviorally salient stimulus is a rapidly approaching (looming) object, which can indicate potential threats [11-13]. Based on findings from humans [14] and nonhuman primates [15, 16] suggesting there to be selective multisensory (auditory-visual) integration of looming signals, we tested whether looming sounds would selectively modulate the excitability of visual cortex. We combined transcranial magnetic stimulation (TMS) over the occipital pole and psychophysics for "neurometric" and psychometric assays of changes in low-level visual cortex excitability (i.e., phosphene induction) and perception, respectively [17, 18]. Across three experiments we show that structured looming sounds considerably enhance visual cortex excitability relative to other sound categories and white-noise controls. The time course of this effect showed that modulation of visual cortex excitability started to differ between looming and stationary sounds for sound portions of very short duration (80 ms) that were significantly below (by 35 ms) perceptual discrimination threshold. Visual perceptions are thus rapidly and efficiently boosted by sounds through early, preperceptual and stimulus-selective modulation of neuronal excitability within low-level visual cortex. © 2009 Elsevier Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: Visual Cortex; Humans; Acoustic Stimulation; Auditory Perception; Sound; Transcranial Magnetic Stimulation
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Faculty of Science and Health
Faculty of Science and Health > Psychology, Department of
SWORD Depositor: Elements
Depositing User: Elements
Date Deposited: 03 May 2013 20:25
Last Modified: 18 Aug 2022 11:31

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