Research Repository

Reproducibility of callosal effects of transcranial magnetic stimulation (TMS) with interhemispheric paired pulses

De Gennaro, L and Ferrara, M and Bertini, M and Pauri, F and Cristiani, R and Curcio, G and Romei, V and Fratello, F and Rossini, PM (2003) 'Reproducibility of callosal effects of transcranial magnetic stimulation (TMS) with interhemispheric paired pulses.' Neuroscience Research, 46 (2). 219 - 227. ISSN 0168-0102

Full text not available from this repository.

Abstract

Transcranial magnetic stimulation (TMS) of the motor cortex of one hemisphere (conditioning stimulus (CS)) inhibits EMG responses evoked in distal hand muscles by a later magnetic stimulus given at an appropriate interval, over the opposite hemisphere (test stimulus (TS)). This effect is commonly attributed to an inhibition produced at cortical level via a transcallosal route. The present study assessed the reproducibility of the transcallosal inhibition effects in different sessions in healthy subjects. Within- and between-subject variability, relating to interhemispheric differences was also evaluated. A magnetic CS on one hemisphere effectively inhibited EMG responses of the abductor digiti minimi stimulated by a TS delivered over the opposite hemisphere in a range of intervals centered at 12 ms. Even though group effects were reproduced in separate sessions, the high between- and within-subject variability yielded low test-retest correlations. This differentiation forces the definition of reproducibility (or repeatability), as the replication of the same mean curves of EMG reduction, and of reliability, as the between- or within-subject correlations between values of specific EMG measures. © 2003 Elsevier Science Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

Item Type: Article
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Faculty of Science and Health > Psychology, Department of
Depositing User: Jim Jamieson
Date Deposited: 12 May 2013 17:53
Last Modified: 17 Aug 2017 18:01
URI: http://repository.essex.ac.uk/id/eprint/5737

Actions (login required)

View Item View Item