Research Repository

Interhemispheric transfer deficit in alexithymia: A transcranial magnetic stimulation study

Romei, V and De Gennaro, L and Fratello, F and Curcio, G and Ferrara, M and Pascual-Leone, A and Bertini, M (2008) 'Interhemispheric transfer deficit in alexithymia: A transcranial magnetic stimulation study.' Psychotherapy and Psychosomatics, 77 (3). 175 - 181. ISSN 0033-3190

Full text not available from this repository.

Abstract

Background: A deficit in interhemispheric transfer was hypothesized in alexithymia more than 30 years ago, following the observation that split-brain patients manifest certain alexithymic characteristics. However, direct evidence of interhemispheric transfer deficit has never been provided. This study investigated the hypothesis of a transcallosal interhemispheric transfer deficit in alexithymia by means of paired-pulse transcranial magnetic stimulation. Methods: A random sample of 300 students was screened for alexithymia using the Italian version of the 20-item Toronto Alexithymia Scale. Eight right-handed males and eight females with high alexithymic scores and an age- and gender-matched group with low alexithymic scores were selected. A first (conditioning) magnetic stimulus was delivered to one motor cortex followed by a second (test) stimulus to the opposite hemisphere at different interstimulus intervals for both motor cortices. Motor evoked responses were recorded from the abductor digit minimi muscles. Results: High alexithymic subjects showed reduced transcallosal inhibition as compared to low alexithymic subjects at interstimulus intervals of 10, 12 and 14 ms in the left-to-right and right-to-left interhemispheric transfer directions. Conclusions: Results point to functional differences in transcallosal interactions in high alexithymic as compared to low alexithymic subjects, supporting the hypothesis of an interhemispheric transfer deficit in alexithymia. Copyright © 2008 S. Karger AG.

Item Type: Article
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Faculty of Science and Health > Psychology, Department of
Depositing User: Jim Jamieson
Date Deposited: 12 May 2013 16:26
Last Modified: 30 Jan 2019 16:16
URI: http://repository.essex.ac.uk/id/eprint/5738

Actions (login required)

View Item View Item