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Cytochrome bd confers nitric oxide resistance to Escherichia coli

Mason, MG and Shepherd, M and Nicholls, P and Dobbin, PS and Dodsworth, KS and Poole, RK and Cooper, CE (2009) 'Cytochrome bd confers nitric oxide resistance to Escherichia coli.' Nature Chemical Biology, 5 (2). 94 - 96. ISSN 1552-4450

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The aerobic respiratory chain of Escherichia coli has two terminal quinol oxidases: cytochrome bo and cytochrome bd. Cytochrome bd was thought to function solely to facilitate micro-aerobic respiration. However, it has recently been shown to be overexpressed under conditions of nitric oxide (NO) stress; we show here that cytochrome bd is crucial for protecting E. coli cells from NO-induced growth inhibition by virtue of its fast NO dissociation rate. © 2009 Nature America, Inc. All rights reserved.

Item Type: Article
Subjects: Q Science > QH Natural history > QH301 Biology
Divisions: Faculty of Science and Health > Life Sciences, School of
Depositing User: Jim Jamieson
Date Deposited: 15 Sep 2011 12:32
Last Modified: 24 Dec 2019 22:15

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