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Gentherapeutische Strategien gegen das kolorektale Karzinom [Gene therapy strategies for colorectal cancer]

Mohr, A and Lyons, M and Mohr, W and Zwacka, RM (2007) 'Gentherapeutische Strategien gegen das kolorektale Karzinom [Gene therapy strategies for colorectal cancer].' Deutsche medizinische Wochenschrift (1946), 132 (11). 567 - 570. ISSN 0012-0472

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Abstract

Current advances in CRC treatment have led to significant but slight improvements in patient survival with curative outcomes only seen in earlier stage cancers. Consequently, much effort is being put into developing completely novel therapies that fulfil a number of criteria including greater efficacy and fewer side effects. Many of these conditions are met by the wide range of gene therapy strategies currently in pre-clinical or clinical trial phases. Gene therapy approaches may be broadly broken down into three main areas: Following a few tragic events in the context of clinical gene therapy studies, safety is currently the prime concern. Further progress in the field is expected from the combination of the described approaches with conventional treatment modalities.

Item Type: Article
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: Faculty of Science and Health > Biological Sciences, School of
Depositing User: Jim Jamieson
Date Deposited: 29 Jun 2017 10:00
Last Modified: 17 Aug 2017 17:55
URI: http://repository.essex.ac.uk/id/eprint/8326

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