Research Repository

Reducing spatial flaws in oligonucleotide arrays by using neighborhood information

Arteaga-Salas, JM and Harrison, AP and Upton, GJG (2008) 'Reducing spatial flaws in oligonucleotide arrays by using neighborhood information.' Statistical Applications in Genetics and Molecular Biology, 7 (1). ISSN 1544-6115

Full text not available from this repository.


We address the problem of detection and correction of spatial flaws in oligonucleotide microarrays. We present two similar procedures, of which one is intended solely for use with replicates and the other has wider applicability. By constructing a set of replicates, with one realistically flawed, we are able to examine the extent to which our procedures are capable of repairing the flaw. We find that, for this purpose, our procedures are superior to the existing 'Harshlight' procedure. Copyright ©2008 The Berkeley Electronic Press. All rights reserved.

Item Type: Article
Subjects: Q Science > QA Mathematics
Q Science > QH Natural history > QH301 Biology
Divisions: Faculty of Science and Health > Mathematical Sciences, Department of
Depositing User: Jim Jamieson
Date Deposited: 04 Oct 2011 13:51
Last Modified: 23 Jan 2019 00:17

Actions (login required)

View Item View Item