Items where Author is "Smith, Steven O"

Article

Sanchez-Reyes, Omar B and Cooke, Aidan LG and Tranter, Dale B and Rashid, Dawood and Eilers, Markus and Reeves, Philip J and Smith, Steven O (2017) G Protein-Coupled Receptors Contain Two Conserved Packing Clusters. Biophysical Journal, 112 (11). pp. 2315-2326. DOI https://doi.org/10.1016/j.bpj.2017.04.051

Kimata, Naoki and Pope, Andreyah and Eilers, Markus and Opefi, Chikwado A and Ziliox, Martine and Hirshfeld, Amiram and Zaitseva, Ekaterina and Vogel, Reiner and Sheves, Mordechai and Reeves, Philip J and Smith, Steven O (2016) Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation. Nature Communications, 7 (1). 12683-. DOI https://doi.org/10.1038/ncomms12683

Kimata, Naoki and Pope, Andreyah and Sanchez-Reyes, Omar B and Eilers, Markus and Opefi, Chikwado A and Ziliox, Martine and Reeves, Philip J and Smith, Steven O (2016) Free backbone carbonyls mediate rhodopsin activation. Nature Structural and Molecular Biology, 23 (8). pp. 738-743. DOI https://doi.org/10.1038/nsmb.3257

Kimata, Naoki and Reeves, Philip J and Smith, Steven O (2015) Uncovering the triggers for GPCR activation using solid-state NMR spectroscopy. Journal of Magnetic Resonance, 253. pp. 111-118. DOI https://doi.org/10.1016/j.jmr.2014.12.014

Opefi, Chikwado A and Tranter, Dale and Smith, Steven O and Reeves, Philip J (2015) Construction of Stable Mammalian Cell Lines for Inducible Expression of G Protein-Coupled Receptors. MEMBRANE PROTEINS - PRODUCTION AND FUNCTIONAL CHARACTERIZATION, 556. pp. 283-305. DOI https://doi.org/10.1016/bs.mie.2014.12.020

Pope, Andreyah and Eilers, Markus and Reeves, Philip J and Smith, Steven O (2014) Amino acid conservation and interactions in rhodopsin: Probing receptor activation by NMR spectroscopy. Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1837 (5). pp. 683-693. DOI https://doi.org/10.1016/j.bbabio.2013.10.007

Opefi, Chikwado A and South, Kieron and Reynolds, Christopher A and Smith, Steven O and Reeves, Philip J (2013) Retinitis Pigmentosa Mutants Provide Insight into the Role of the N-terminal Cap in Rhodopsin Folding, Structure, and Function. Journal of Biological Chemistry, 288 (47). pp. 33912-33926. DOI https://doi.org/10.1074/jbc.m113.483032

Arakawa, Makoto and Chakraborty, Raja and Upadhyaya, Jasbir and Eilers, Markus and Reeves, Philip J and Smith, Steven O and Chelikani, Prashen (2011) Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β2-adrenergic receptor. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1808 (4). pp. 1170-1178. DOI https://doi.org/10.1016/j.bbamem.2011.01.012

Goncalves, Joseph A and South, Kieron and Ahuja, Shivani and Zaitseva, Ekaterina and Opefi, Chikwado A and Eilers, Markus and Vogel, Reiner and Reeves, Philip J and Smith, Steven O (2010) Highly conserved tyrosine stabilizes the active state of rhodopsin. Proceedings of the National Academy of Sciences, 107 (46). pp. 19861-19866. DOI https://doi.org/10.1073/pnas.1009405107

Hornak, Viktor and Ahuja, Shivani and Eilers, Markus and Goncalves, Joseph A and Sheves, Mordechai and Reeves, Philip J and Smith, Steven O (2010) Light Activation of Rhodopsin: Insights from Molecular Dynamics Simulations Guided by Solid-State NMR Distance Restraints. Journal of Molecular Biology, 396 (3). pp. 510-527. DOI https://doi.org/10.1016/j.jmb.2009.12.003

Ahuja, Shivani and Crocker, Evan and Eilers, Markus and Hornak, Viktor and Hirshfeld, Amiram and Ziliox, Martine and Syrett, Natalie and Reeves, Philip J and Khorana, H Gobind and Sheves, Mordechai and Smith, Steven O (2009) Location of the Retinal Chromophore in the Activated State of Rhodopsin. Journal of Biological Chemistry, 284 (15). pp. 10190-10201. DOI https://doi.org/10.1074/jbc.m805725200

Ahuja, Shivani and Hornak, Viktor and Yan, Elsa CY and Syrett, Natalie and Goncalves, Joseph A and Hirshfeld, Amiram and Ziliox, Martine and Sakmar, Thomas P and Sheves, Mordechai and Reeves, Philip J and Smith, Steven O and Eilers, Markus (2009) Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation. Nature Structural & Molecular Biology, 16 (2). pp. 168-175. DOI https://doi.org/10.1038/nsmb.1549