Umeton, Renato and Stracquadanio, Giovanni and Sorathiya, Anilkumar and Liò, Pietro and Papini, Alessio and Nicosia, Giuseppe (2011) Design of robust metabolic pathways. In: DAC '11: The 48th Annual Design Automation Conference 2011, ? - ?.
Umeton, Renato and Stracquadanio, Giovanni and Sorathiya, Anilkumar and Liò, Pietro and Papini, Alessio and Nicosia, Giuseppe (2011) Design of robust metabolic pathways. In: DAC '11: The 48th Annual Design Automation Conference 2011, ? - ?.
Umeton, Renato and Stracquadanio, Giovanni and Sorathiya, Anilkumar and Liò, Pietro and Papini, Alessio and Nicosia, Giuseppe (2011) Design of robust metabolic pathways. In: DAC '11: The 48th Annual Design Automation Conference 2011, ? - ?.
Abstract
In this paper we investigate plant photosynthesis and microbial fuel cells. We report the following: 1) we introduce and validate a novel multi-objective optimization algorithm, PMO2; 2) in photosynthesis we increase the yield of 135%, while in Geobacter sulfurreducens we determine the tradeoff for growth versus redox properties; 3) finally, we discuss Pareto-Front as an estimator of robust metabolic pathways. © 2011 ACM.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Additional Information: | Published proceedings: Proceedings - Design Automation Conference |
| Uncontrolled Keywords: | Metabolic engineering; Mutational Robustness; Geobacter sulfurreducens; Carbon metabolism; Multi-objective Optimization |
| Subjects: | Q Science > QA Mathematics > QA75 Electronic computers. Computer science |
| Divisions: | Faculty of Science and Health Faculty of Science and Health > Computer Science and Electronic Engineering, School of |
| SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
| Depositing User: | Unnamed user with email elements@essex.ac.uk |
| Date Deposited: | 13 Feb 2017 13:33 |
| Last Modified: | 05 Dec 2024 21:40 |
| URI: | http://repository.essex.ac.uk/id/eprint/18707 |