Nicosia, Giuseppe and Stracquadanio, Giovanni (2007) Generalized Pattern Search and Mesh Adaptive Direct Search Algorithms for Protein Structure Prediction. In: UNSPECIFIED, ? - ?.
Nicosia, Giuseppe and Stracquadanio, Giovanni (2007) Generalized Pattern Search and Mesh Adaptive Direct Search Algorithms for Protein Structure Prediction. In: UNSPECIFIED, ? - ?.
Nicosia, Giuseppe and Stracquadanio, Giovanni (2007) Generalized Pattern Search and Mesh Adaptive Direct Search Algorithms for Protein Structure Prediction. In: UNSPECIFIED, ? - ?.
Abstract
Proteins are the most important molecular entities of a living organism and understanding their functions is an important task to treat diseases and synthesize new drugs. It is largely known that the function of a protein is strictly related to its spatial conformation: to tackle this problem, we have proposed a new approach based on a class of pattern search algorithms that is largely used in optimization of real world applications. The obtained results are interesting in terms of the quality of the structures (RMSD-C α) and energy values found. © Springer-Verlag Berlin Heidelberg 2007.
| Item Type: | Conference or Workshop Item (UNSPECIFIED) |
|---|---|
| Additional Information: | Published proceedings: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) |
| Uncontrolled Keywords: | protein folding; pattern search algorithms; non-linear optimization |
| Subjects: | Q Science > QA Mathematics > QA75 Electronic computers. Computer science |
| Divisions: | Faculty of Science and Health Faculty of Science and Health > Computer Science and Electronic Engineering, School of |
| SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
| Depositing User: | Unnamed user with email elements@essex.ac.uk |
| Date Deposited: | 13 Feb 2017 15:05 |
| Last Modified: | 23 Sep 2022 18:43 |
| URI: | http://repository.essex.ac.uk/id/eprint/18718 |