Quint, Jennifer K and Moore, Elisabeth and Lewis, Adam and Hashmi, Maimoona and Sultana, Kirin and Wright, Mark and Smeeth, Liam and Chatzidiakou, Lia and Jones, Roderic and Beevers, Sean and Kolozali, Sefki and Kelly, Frank and Barratt, Benjamin (2018) Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research. npj Primary Care Respiratory Medicine, 28 (1). 21-. DOI https://doi.org/10.1038/s41533-018-0089-3
Quint, Jennifer K and Moore, Elisabeth and Lewis, Adam and Hashmi, Maimoona and Sultana, Kirin and Wright, Mark and Smeeth, Liam and Chatzidiakou, Lia and Jones, Roderic and Beevers, Sean and Kolozali, Sefki and Kelly, Frank and Barratt, Benjamin (2018) Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research. npj Primary Care Respiratory Medicine, 28 (1). 21-. DOI https://doi.org/10.1038/s41533-018-0089-3
Quint, Jennifer K and Moore, Elisabeth and Lewis, Adam and Hashmi, Maimoona and Sultana, Kirin and Wright, Mark and Smeeth, Liam and Chatzidiakou, Lia and Jones, Roderic and Beevers, Sean and Kolozali, Sefki and Kelly, Frank and Barratt, Benjamin (2018) Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research. npj Primary Care Respiratory Medicine, 28 (1). 21-. DOI https://doi.org/10.1038/s41533-018-0089-3
Abstract
Databases of electronic health records (EHR) are not only a valuable source of data for health research but have also recently been used as a medium through which potential study participants can be screened, located and approached to take part in research. The aim was to assess whether it is feasible and practical to screen, locate and approach patients to take part in research through the Clinical Practice Research Datalink (CPRD). This is a cohort study in primary care. The CPRD anonymised EHR database was searched to screen patients with Chronic Obstructive Pulmonary Disease (COPD) to take part in a research study. The potential participants were contacted via their General Practitioner (GP) who confirmed their eligibility. Eighty two practices across Greater London were invited to the study. Twenty-six (31.7%) practices consented to participate resulting in a pre-screened list of 988 patients. Of these, 632 (63.7%) were confirmed as eligible following the GP review. Two hundred twenty seven (36%) response forms were received by the study team; 79 (34.8%) responded ‘yes’ (i.e., they wanted to be contacted by the research assistant for more information and to talk about enrolling in the study), and 148 (65.2%) declined participation. This study has shown that it is possible to use EHR databases such as CPRD to screen, locate and recruit participants for research. This method provides access to a cohort of patients while minimising input needed by GPs and allows researchers to examine healthcare usage and disease burden in more detail and in real-life settings.
Item Type: | Article |
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Uncontrolled Keywords: | Humans; Pulmonary Disease, Chronic Obstructive; Biomedical Research; Patient Selection; Electronic Health Records |
Subjects: | R Medicine > R Medicine (General) Z Bibliography. Library Science. Information Resources > ZA Information resources > ZA4050 Electronic information resources |
Divisions: | Faculty of Science and Health Faculty of Science and Health > Computer Science and Electronic Engineering, School of |
SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
Depositing User: | Unnamed user with email elements@essex.ac.uk |
Date Deposited: | 20 Nov 2018 14:17 |
Last Modified: | 07 Aug 2024 18:50 |
URI: | http://repository.essex.ac.uk/id/eprint/23503 |
Available files
Filename: Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research.pdf
Licence: Creative Commons: Attribution 3.0