Bleich, S and Jünemann, A and von Ahsen, N and Lausen, B and Ritter, K and Beck, G and Naumann, GOH and Kornhuber, J (2002) Homocysteine and risk of open-angle glaucoma. Journal of Neural Transmission, 109 (12). pp. 1499-1504. DOI https://doi.org/10.1007/s007020200097
Bleich, S and Jünemann, A and von Ahsen, N and Lausen, B and Ritter, K and Beck, G and Naumann, GOH and Kornhuber, J (2002) Homocysteine and risk of open-angle glaucoma. Journal of Neural Transmission, 109 (12). pp. 1499-1504. DOI https://doi.org/10.1007/s007020200097
Bleich, S and Jünemann, A and von Ahsen, N and Lausen, B and Ritter, K and Beck, G and Naumann, GOH and Kornhuber, J (2002) Homocysteine and risk of open-angle glaucoma. Journal of Neural Transmission, 109 (12). pp. 1499-1504. DOI https://doi.org/10.1007/s007020200097
Abstract
Homocysteine levels and the frequency of heterozygous methylenetetrahydrofolate reductase (MTHFR) C677T mutation are increased in open-angle glaucoma. Since homocysteine can induce vascular injury, alterations in extracellular matrix remodelling, and neuronal cell death, these findings may have important implications for understanding glaucomatous optic neuropathy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Glaucoma; homocysteine; MTHFR polymorphism; glaucomatous optic neuropathy |
| Subjects: | R Medicine > RE Ophthalmology |
| Divisions: | Faculty of Science and Health Faculty of Science and Health > Mathematics, Statistics and Actuarial Science, School of |
| SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
| Depositing User: | Unnamed user with email elements@essex.ac.uk |
| Date Deposited: | 04 Jul 2012 20:47 |
| Last Modified: | 05 Dec 2024 19:00 |
| URI: | http://repository.essex.ac.uk/id/eprint/2500 |