Castro-Gutierrez, Victor and Hassard, Francis and Vu, Milan and Leitao, Rodrigo and Burczynska, Beata and Wildeboer, Dirk and Stanton, Isobel and Rahimzadeh, Shadi and Baio, Ginaluca and Garelick, Hemda and Hofman, Jan and Kasprzyk-Hordern, Barbara and Majeed, Azeem and Priest, Sally and Grimsley, Jasmine and Singer, Andrew C and Lundy, Lian and Di Cesare, Mariachiara (2022) Monitoring occurrence of SARS-CoV-2 in school populations: a wastewater-based approach. PLoS One, 17 (6). e0270168-e0270168. DOI https://doi.org/10.1371/journal.pone.0270168 (In Press)
Castro-Gutierrez, Victor and Hassard, Francis and Vu, Milan and Leitao, Rodrigo and Burczynska, Beata and Wildeboer, Dirk and Stanton, Isobel and Rahimzadeh, Shadi and Baio, Ginaluca and Garelick, Hemda and Hofman, Jan and Kasprzyk-Hordern, Barbara and Majeed, Azeem and Priest, Sally and Grimsley, Jasmine and Singer, Andrew C and Lundy, Lian and Di Cesare, Mariachiara (2022) Monitoring occurrence of SARS-CoV-2 in school populations: a wastewater-based approach. PLoS One, 17 (6). e0270168-e0270168. DOI https://doi.org/10.1371/journal.pone.0270168 (In Press)
Castro-Gutierrez, Victor and Hassard, Francis and Vu, Milan and Leitao, Rodrigo and Burczynska, Beata and Wildeboer, Dirk and Stanton, Isobel and Rahimzadeh, Shadi and Baio, Ginaluca and Garelick, Hemda and Hofman, Jan and Kasprzyk-Hordern, Barbara and Majeed, Azeem and Priest, Sally and Grimsley, Jasmine and Singer, Andrew C and Lundy, Lian and Di Cesare, Mariachiara (2022) Monitoring occurrence of SARS-CoV-2 in school populations: a wastewater-based approach. PLoS One, 17 (6). e0270168-e0270168. DOI https://doi.org/10.1371/journal.pone.0270168 (In Press)
Abstract
Clinical testing of children in schools is challenging, with economic implications limiting its frequent use as a monitoring tool of the risks assumed by children and staff during the COVID-19 pandemic. Here, a wastewater-based epidemiology approach has been used to monitor 16 schools (10 primary, 5 secondary and 1 post-16 and further education) in England. A total of 296 samples over 9 weeks have been analysed for N1 and E genes using qPCR methods. Of the samples returned, 47.3% were positive for one or both genes with a detection frequency in line with the respective local community. WBE offers a low cost, non-invasive approach for supplementing clinical testing and can provide longitudinal insights that are impractical with traditional clinical testing.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Humans; Schools; Child; Pandemics; COVID-19; SARS-CoV-2; Wastewater |
| Divisions: | Faculty of Science and Health Faculty of Science and Health > Health and Social Care, School of |
| SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
| Depositing User: | Unnamed user with email elements@essex.ac.uk |
| Date Deposited: | 10 Aug 2022 08:27 |
| Last Modified: | 30 Oct 2024 20:48 |
| URI: | http://repository.essex.ac.uk/id/eprint/32984 |
Available files
Filename: journal.pone.0270168.pdf
Licence: Creative Commons: Attribution 3.0