Moghanizadeh, A and Khaksar, H and Kafash Hoshiar, Ali (2023) A novel non-invasive intervention for removing occlusions from shunts using an abrading magnetic microswarm. IEEE Transactions on Biomedical Engineering, 70 (2). pp. 413-422. DOI https://doi.org/10.1109/tbme.2022.3192807
Moghanizadeh, A and Khaksar, H and Kafash Hoshiar, Ali (2023) A novel non-invasive intervention for removing occlusions from shunts using an abrading magnetic microswarm. IEEE Transactions on Biomedical Engineering, 70 (2). pp. 413-422. DOI https://doi.org/10.1109/tbme.2022.3192807
Moghanizadeh, A and Khaksar, H and Kafash Hoshiar, Ali (2023) A novel non-invasive intervention for removing occlusions from shunts using an abrading magnetic microswarm. IEEE Transactions on Biomedical Engineering, 70 (2). pp. 413-422. DOI https://doi.org/10.1109/tbme.2022.3192807
Abstract
Objective: Shunts are often employed as internal medical devices for draining aberrant fluids from organs. However, depositions of calcification in the shunt walls lead to its failure, requiring frequent replacements. The current surgical procedures for implanting shunts are invasive. Methods: This paper introduces a novel, non-invasive approach for eliminating shunt deposits. In this non-invasive intervention, a swarm of magnetic nanoparticles (MNPs) guided by an external magnetic field removes the shunt deposition. A prototype device was fabricated to provide a proof of concept. MNPs were steered within the shunt channel containing calcification layers and successfully abraded the deposition layer. The proof-of-concept experiments used a moving magnetic field ranging from 0.1 to 0.3 T and a velocity between 1 to 12 cm/s. The average nanoparticles size was 45nm. Five diverse contact theories predicted the amount of wear and indentation depth created by the abrading microswarm. Results: Experimental results confirm that MNPs under a moving magnetic field can abrade shunt deposits. Also, there is a direct relation between the intensity of the magnetic field, the speed of magnet movement, and the rate of abrading the calcification deposits. The simulation results showed that the Hoeprich model deviated 12.1% from the experimental results and was the most suitable model. Conclusion & significance: This research has introduced a novel minimally invasive approach to remove shunt depositions that can reduce the number of revision surgeries and prevent surgical complications.
Item Type: | Article |
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Uncontrolled Keywords: | Calcification; Non-invasive method; Shunt deposit; Steering; Swarm of magnetic nanoparticles |
Divisions: | Faculty of Science and Health Faculty of Science and Health > Computer Science and Electronic Engineering, School of |
SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
Depositing User: | Unnamed user with email elements@essex.ac.uk |
Date Deposited: | 08 Aug 2022 16:51 |
Last Modified: | 07 Aug 2024 20:15 |
URI: | http://repository.essex.ac.uk/id/eprint/33225 |
Available files
Filename: Final version-R2.pdf