Trajkovic, Jelena and Romei, Vincenzo and Rushworth, Matthew FS and Sel, Alejandra (2023) Changing connectivity between premotor and motor cortex changes inter-areal communication in the human brain. Progress in Neurobiology, 228. p. 102487. DOI https://doi.org/10.1016/j.pneurobio.2023.102487
Trajkovic, Jelena and Romei, Vincenzo and Rushworth, Matthew FS and Sel, Alejandra (2023) Changing connectivity between premotor and motor cortex changes inter-areal communication in the human brain. Progress in Neurobiology, 228. p. 102487. DOI https://doi.org/10.1016/j.pneurobio.2023.102487
Trajkovic, Jelena and Romei, Vincenzo and Rushworth, Matthew FS and Sel, Alejandra (2023) Changing connectivity between premotor and motor cortex changes inter-areal communication in the human brain. Progress in Neurobiology, 228. p. 102487. DOI https://doi.org/10.1016/j.pneurobio.2023.102487
Abstract
The ventral premotor cortex (PMv) is an important component of cortico-cortical pathways mediating prefrontal control over primary motor cortex (M1) function. Paired associative stimulation (ccPAS) is known to change PMv influence over M1 in humans, which manifests differently depending on the behavioural context. Here we show that these changes in influence are functionally linked to PMv-M1 phase synchrony changes induced by repeated paired stimulation of the two areas. PMv-to-M1 ccPAS leads to increased phase synchrony in alpha and beta bands, while reversed order M1-to-PMv ccPAS leads to decreased theta phase synchrony. These changes are visible at rest but are predictive of changes in oscillatory power in the same frequencies during movement execution and inhibition, respectively. The results unveil a link between the physiology of the motor network and the resonant frequencies mediating its interactions and provide a putative mechanism underpinning the relationship between synaptic efficacy and brain oscillations.
Item Type: | Article |
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Uncontrolled Keywords: | Transcranial magnetic stimulation; Ventral pre-motor cortex; Primary motor cortex; Cortico-cortical paired associative stimulation; Oscillations; Communication through coherence |
Divisions: | Faculty of Science and Health Faculty of Science and Health > Psychology, Department of |
SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
Depositing User: | Unnamed user with email elements@essex.ac.uk |
Date Deposited: | 25 Jul 2023 10:50 |
Last Modified: | 16 May 2024 21:55 |
URI: | http://repository.essex.ac.uk/id/eprint/35965 |
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