Ronald, Angelica and Gui, Anna (2024) The potential and translational application of infant genetic research. Nature Genetics, 56 (7). pp. 1346-1354. DOI https://doi.org/10.1038/s41588-024-01822-7
Ronald, Angelica and Gui, Anna (2024) The potential and translational application of infant genetic research. Nature Genetics, 56 (7). pp. 1346-1354. DOI https://doi.org/10.1038/s41588-024-01822-7
Ronald, Angelica and Gui, Anna (2024) The potential and translational application of infant genetic research. Nature Genetics, 56 (7). pp. 1346-1354. DOI https://doi.org/10.1038/s41588-024-01822-7
Abstract
In the current genomic revolution, the infancy life stage is the most neglected. Although clinical genetics recognizes the value of early identification in infancy of rare genetic causes of disorders and delay, common genetic variation is almost completely ignored in research on infant behavioral and neurodevelopmental traits. In this Perspective, we argue for a much-needed surge in research on common genetic variation influencing infant neurodevelopment and behavior, findings that would be relevant for all children. We now see convincing evidence from different research designs to suggest that developmental milestones, skills and behaviors of infants are heritable and thus are suitable candidates for gene-discovery research. We highlight the resources available to the field, including genotyped infant cohorts, and we outline, with recommendations, special considerations needed for infant data. Therefore, infant genetic research has the potential to impact basic science and to affect educational policy, public health and clinical practice.
Item Type: | Article |
---|---|
Uncontrolled Keywords: | Child Development; Genetic Research; Genetic Variation; Humans; Infant; Infant, Newborn; Translational Research, Biomedical |
Divisions: | Faculty of Science and Health Faculty of Science and Health > Psychology, Department of |
SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
Depositing User: | Unnamed user with email elements@essex.ac.uk |
Date Deposited: | 24 Sep 2024 11:43 |
Last Modified: | 30 Oct 2024 21:33 |
URI: | http://repository.essex.ac.uk/id/eprint/39018 |