Items where Author is "Brooke, GN"

Leach, DA and Mohr, A and Giotis, ES and Cil, E and Isac, AM and Yates, LL and Barclay, WS and Zwacka, RM and Bevan, CL and Brooke, GN (2021) The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells. Nature Communications, 12 (1). 4068-. DOI https://doi.org/10.1038/s41467-021-24342-y

Fioretti, FM and Sita-Lumsden, A and Bevan, CL and Brooke, GN (2014) Revising the role of the androgen receptor in breast cancer. Journal of Molecular Endocrinology, 52 (3). R257-R265. DOI https://doi.org/10.1530/jme-14-0030

Dart, DA and Brooke, GN and Sita-Lumsden, A and Waxman, J and Bevan, CL (2012) Reducing prohibitin increases histone acetylation, and promotes androgen independence in prostate tumours by increasing androgen receptor activation by adrenal androgens. Oncogene, 31 (43). pp. 4588-4598. DOI https://doi.org/10.1038/onc.2011.591

Brooke, GN and Parker, MG and Bevan, CL (2008) Mechanisms of androgen receptor activation in advanced prostate cancer: differential co-activator recruitment and gene expression. Oncogene, 27 (21). pp. 2941-2950. DOI https://doi.org/10.1038/sj.onc.1210955

Gamble, SC and Chotai, D and Odontiadis, M and Dart, DA and Brooke, GN and Powell, SM and Reebye, V and Varela-Carver, A and Kawano, Y and Waxman, J and Bevan, CL (2007) Prohibitin, a protein downregulated by androgens, represses androgen receptor activity. Oncogene, 26 (12). pp. 1757-1768. DOI https://doi.org/10.1038/sj.onc.1209967

Powell, SM and Brooke, GN and Whitaker, HC and Reebye, V and Gamble, SC and Chotai, D and Dart, DA and Belandia, B and Bevan, CL (2006) Mechanisms of androgen receptor repression in prostate cancer. Biochemical Society Transactions, 34 (6). pp. 1124-1127. DOI https://doi.org/10.1042/bst0341124