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Items where Author is "Christopoulos, Arthur"

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Number of items: 9.

Article

Dong, Maoqing and Deganutti, Giuseppe and Piper, Sarah J and Liang, Yi-Lynn and Khoshouei, Maryam and Belousoff, Matthew J and Harikumar, Kaleeckal G and Reynolds, Christopher A and Glukhova, Alisa and Furness, Sebastian GB and Christopoulos, Arthur and Danev, Radostin and Wootten, Denise and Sexton, Patrick M and Miller, Laurence J (2020) 'Structure and dynamics of the active Gs-coupled human secretin receptor.' Nature Communications, 11 (1). 4137-. ISSN 2041-1723

Zhao, Peishen and Liang, Yi-Lynn and Belousoff, Matthew J and Deganutti, Giuseppe and Fletcher, Madeleine M and Willard, Francis S and Bell, Michael G and Christe, Michael E and Sloop, Kyle W and Inoue, Asuka and Truong, Tin T and Clydesdale, Lachlan and Furness, Sebastian GB and Christopoulos, Arthur and Wang, Ming-Wei and Miller, Laurence J and Reynolds, Christopher A and Danev, Radostin and Sexton, Patrick M and Wootten, Denise (2020) 'Activation of the GLP-1 receptor by a non-peptidic agonist.' Nature, 577 (7790). pp. 432-436. ISSN 0028-0836

Pham, Vi and Zhu, Yue and Dal Maso, Emma and Reynolds, Christopher A and Deganutti, Giuseppe and Atanasio, Silvia and Hick, Caroline A and Yang, Dehua and Christopoulos, Arthur and Hay, Debbie L and Furness, Sebastian GB and Wang, Ming-Wei and Wootten, Denise and Sexton, Patrick M (2019) 'Deconvoluting the Molecular Control of Binding and Signaling at the Amylin 3 Receptor: RAMP3 Alters Signal Propagation through Extracellular Loops of the Calcitonin Receptor.' ACS Pharmacology and Translational Science, 2 (3). pp. 183-197. ISSN 2575-9108

dal Maso, Emma and Glukhova, Alisa and Zhu, Yue and Garcia-Nafria, Javier and Tate, Christopher G and Atanasio, Silvia and Reynolds, Christopher A and Ramírez-Aportela, Erney and Carazo, Jose-Maria and Hick, Caroline A and Furness, Sebastian GB and Hay, Debbie L and Liang, Yi-Lynn and Miller, Laurence J and Christopoulos, Arthur and Wang, Ming-Wei and Wootten, Denise and Sexton, Patrick M (2019) 'The Molecular Control of Calcitonin Receptor Signaling.' ACS Pharmacology & Translational Science, 2 (1). pp. 31-51. ISSN 2575-9108

Liang, Yi-Lynn and Khoshouei, Maryam and Deganutti, Giuseppe and Glukhova, Alisa and Koole, Cassandra and Peat, Thomas S and Radjainia, Mazdak and Plitzko, Jürgen M and Baumeister, Wolfgang and Miller, Laurence J and Hay, Deborah L and Christopoulos, Arthur and Reynolds, Christopher A and Wootten, Denise and Sexton, Patrick M (2018) 'Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor.' Nature, 561 (7724). pp. 492-497. ISSN 0028-0836

Dal Maso, Emma and Zhu, Yue and Pham, Vi and Reynolds, Christopher A and Deganutti, Giuseppe and Hick, Caroline A and Yang, Dehua and Christopoulos, Arthur and Hay, Debbie L and Wang, Ming-Wei and Sexton, Patrick M and Furness, Sebastian GB and Wootten, Denise (2018) 'Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy.' Biochemical Pharmacology, 150. pp. 214-244. ISSN 0006-2952

Wootten, Denise and Reynolds, Christopher A and Smith, Kevin J and Mobarec, Juan C and Furness, Sebastian GB and Miller, Laurence J and Christopoulos, Arthur and Sexton, Patrick M (2016) 'Key interactions by conserved polar amino acids located at the transmembrane helical boundaries in Class B GPCRs modulate activation, effector specificity and biased signalling in the glucagon-like peptide-1 receptor.' Biochemical Pharmacology, 118. pp. 68-87. ISSN 0006-2952

Wootten, Denise and Reynolds, Christopher A and Smith, Kevin J and Mobarec, Juan C and Koole, Cassandra and Savage, Emilia E and Pabreja, Kavita and Simms, John and Sridhar, Rohan and Furness, Sebastian GB and Liu, Mengjie and Thompson, Philip E and Miller, Laurence J and Christopoulos, Arthur and Sexton, Patrick M (2016) 'The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism.' Cell, 165 (7). pp. 1632-1643. ISSN 0092-8674

Wootten, Denise and Reynolds, Christopher A and Koole, Cassandra and Smith, Kevin J and Mobarec, Juan C and Simms, John and Quon, Tezz and Coudrat, Thomas and Furness, Sebastian GB and Miller, Laurence J and Christopoulos, Arthur and Sexton, Patrick M (2016) 'A Hydrogen-Bonded Polar Network in the Core of the Glucagon-Like Peptide-1 Receptor Is a Fulcrum for Biased Agonism: Lessons from Class B Crystal Structures.' Molecular Pharmacology, 89 (3). pp. 335-347. ISSN 0026-895X

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