Items where Author is "Coombes, R Charles"
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Rudraraju, Bharath and Droog, Marjolein and Abdel-Fatah, Tarek MA and Zwart, Wilbert and Giannoudis, Athina and Malki, Mohammed I and Moore, David and Patel, Hetal and Shaw, Jacqui and Ellis, Ian O and Chan, Steve and Brooke, Greg N and Nevedomskaya, Ekaterina and Nigro, Christiana Lo and Carroll, Jason and Coombes, R Charles and Bevan, Charlotte and Ali, Simak and Palmieri, Carlo (2014) Phosphorylation of activating transcription factor-2 (ATF-2) within the activation domain is a key determinant of sensitivity to tamoxifen in breast cancer. Breast Cancer Research and Treatment, 147 (2). pp. 295-309. DOI https://doi.org/10.1007/s10549-014-3098-0
Vigushin, David M and Brooke, Greg and Willows, David and Coombes, R Charles and Moody, Christopher J (2003) Pyrazino[1,2- a ]indole-1,4-diones, simple analogues of gliotoxin, as selective inhibitors of geranylgeranyltransferase I. Bioorganic & Medicinal Chemistry Letters, 13 (21). pp. 3661-3663. DOI https://doi.org/10.1016/j.bmcl.2003.08.022
Marson, Charles M and Rioja, Alphonso S and Brooke, Greg and Coombes, R Charles and Vigushin, David M (2002) Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase. Bioorganic & Medicinal Chemistry Letters, 12 (2). pp. 255-259. DOI https://doi.org/10.1016/s0960-894x(01)00718-1