Items where Author is "Hough, Michael A"
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Bolton, Rachel and Machelett, Moritz M and Worrall, Jonathan AR and Hough, Michael A and et al. (2024) A redox switch allows binding of Fe(II) and Fe(III) ions in the cyanobacterial iron-binding protein FutA from Prochlorococcus. Proceedings of the National Academy of Sciences of the United States of America, 121 (12). e2308478121-. DOI https://doi.org/10.1073/pnas.2308478121
Adams, Hannah R and Svistunenko, Dimitri A and Wilson, Michael T and Fujii, Sotaro and Strange, Richard W and Hardy, Zoe A and Vazquez, Priscilla A and Dabritz, Tyler and Streblow, Gabriel J and Andrew, Colin R and Hough, Michael A (2023) A heme pocket aromatic quadrupole modulates gas binding to cytochrome c'-β: Implications for NO sensors. Journal of Biological Chemistry, 299 (6). p. 104742. DOI https://doi.org/10.1016/j.jbc.2023.104742
Worrall, Jonathan AR and Hough, Michael A (2022) Serial femtosecond crystallography approaches to understanding catalysis in iron enzymes. Current Opinion in Structural Biology, 77. p. 102486. DOI https://doi.org/10.1016/j.sbi.2022.102486
LuÄiÄ, Marina and Wilson, Michael T and Tosha, Takehiko and Sugimoto, Hiroshi and Shilova, Anastasya and Axford, Danny and Owen, Robin L and Hough, Michael A and Worrall, Jonathan AR (2022) Serial Femtosecond Crystallography Reveals the Role of Water in the One- or Two-Electron Redox Chemistry of Compound i in the Catalytic Cycle of the B-Type Dye-Decolorizing Peroxidase DtpB. ACS Catalysis, 12 (21). pp. 13349-13359. DOI https://doi.org/10.1021/acscatal.2c03754
Moreno-Chicano, Tadeo and Carey, Leiah M and Axford, Danny and Beale, John H and Doak, R Bruce and Duyvesteyn, Helen ME and Ebrahim, Ali and Henning, Robert W and Monteiro, Diana CF and Myles, Dean A and Owada, Shigeki and Sherrell, Darren A and Straw, Megan L and Ĺ rajer, Vukica and Sugimoto, Hiroshi and Tono, Kensuke and Tosha, Takehiko and Tews, Ivo and Trebbin, Martin and Strange, Richard W and Weiss, Kevin L and Worrall, Jonathan AR and Meilleur, Flora and Owen, Robin L and Ghiladi, Reza A and Hough, Michael A (2022) Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature. IUCrJ, 9 (5). pp. 610-624. DOI https://doi.org/10.1107/s2052252522006418
Hough, Michael A and Owen, Robin L (2021) Serial synchrotron and XFEL crystallography for studies of metalloprotein catalysis. Current Opinion in Structural Biology, 71. pp. 232-238. DOI https://doi.org/10.1016/j.sbi.2021.07.007
LuÄiÄ, Marina and Wilson, Michael T and Svistunenko, Dimitri A and Owen, Robin L and Hough, Michael A and Worrall, Jonathan AR (2021) Aspartate or arginine? Validated redox state X-ray structures elucidate mechanistic subtleties of FeIVâ=âO formation in bacterial dye-decolorizing peroxidases. Journal of Biological Inorganic Chemistry, 26 (7). pp. 743-761. DOI https://doi.org/10.1007/s00775-021-01896-2
Sen, Kakali and Hough, Michael A and Strange, Richard W and Yong, Chin and Keal, Thomas W (2021) QM/MM Simulations of Protein Crystal Reactivity Guided by MSOX Crystallography: A Copper Nitrite Reductase Case Study. The Journal of Physical Chemistry B: Biophysical Chemistry, Biomaterials, Liquids, and Soft Matter, 125 (32). pp. 9102-9114. DOI https://doi.org/10.1021/acs.jpcb.1c03661
McKew, Boyd A and Johnson, Richard and Clothier, Lindsay and Skeels, Karl and Ross, Matthew S and Metodiev, Metodi and Frenzel, Max and Gieg, Lisa M and Martin, Jonathan W and Hough, Michael A and Whitby, Corinne (2021) Differential protein expression during growth on model and commercial mixtures of naphthenic acids in Pseudomonas fluorescens Pfâ5. MicrobiologyOpen, 10 (4). e1196-. DOI https://doi.org/10.1002/mbo3.1196
Horrell, Sam and Axford, Danny and Devenish, Nicholas E and Ebrahim, Ali and Hough, Michael A and Sherrell, Darren A and Storm, Selina LS and Tews, Ivo and Worrall, Jonathan AR and Owen, Robin L (2021) Fixed Target Serial Data Collection at Diamond Light Source. Journal of Visualized Experiments, 2021 (168). DOI https://doi.org/10.3791/62200
Beale, John H and Bolton, Rachel and Marshall, Stephen A and Beale, Emma V and Carr, Stephen B and Ebrahim, Ali and Moreno-Chicano, Tadeo and Hough, Michael A and Worrall, Jonathan AR and Tews, Ivo and Owen, Robin L (2019) Successful sample preparation for serial crystallography experiments. Journal of Applied Crystallography, 52 (6). pp. 1385-1396. DOI https://doi.org/10.1107/s1600576719013517
Moreno-Chicano, Tadeo and Ebrahim, Ali and Axford, Danny and Appleby, Martin V and Beale, John H and Chaplin, Amanda K and Duyvesteyn, Helen ME and Ghiladi, Reza A and Owada, Shigeki and Sherrell, Darren A and Strange, Richard W and Sugimoto, Hiroshi and Tono, Kensuke and Worrall, Jonathan AR and Owen, Robin L and Hough, Michael A (2019) High-throughput structures of proteinâligand complexes at room temperature using serial femtosecond crystallography. IUCrJ, 6 (6). pp. 1074-1085. DOI https://doi.org/10.1107/s2052252519011655
Straw, Megan L and Hough, Michael A and Wilson, Michael T and Worrall, Jonathan AR (2019) A histidine residue and a tetranuclear cuprousâthiolate cluster dominate the copper loading landscape of a copper storage protein from Streptomyces lividans. Chemistry â A European Journal, 25 (45). pp. 10678-10688. DOI https://doi.org/10.1002/chem.201901411
Ebrahim, Ali and Moreno-Chicano, Tadeo and Appleby, Martin V and Chaplin, Amanda K and Beale, John H and Sherrell, Darren A and Duyvesteyn, Helen ME and Owada, Shigeki and Tono, Kensuke and Sugimoto, Hiroshi and Strange, Richard W and Worrall, Jonathan AR and Axford, Danny and Owen, Robin L and Hough, Michael A (2019) Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins. IUCrJ, 6 (4). pp. 543-551. DOI https://doi.org/10.1107/s2052252519003956
Chaplin, Amanda K and Chicano, Tadeo Moreno and Hampshire, Bethany V and Wilson, Michael T and Hough, Michael A and Svistunenko, Dimitri A and Worrall, Jonathan AR (2019) An Aromatic Dyad Motif in Dye Decolourising Peroxidases Has Implications for Free Radical Formation and Catalysis. Chemistry â A European Journal, 25 (24). pp. 6141-6153. DOI https://doi.org/10.1002/chem.201806290
Ebrahim, Ali and Appleby, Martin V and Axford, Danny and Beale, John and Moreno-Chicano, Tadeo and Sherrell, Darren A and Strange, Richard W and Hough, Michael A and Owen, Robin L (2019) Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography. Acta Crystallographica Section D Structural Biology, 75 (2). pp. 151-159. DOI https://doi.org/10.1107/s2059798318010240
Adams, Hannah R and Krewson, Callie and Vardanega, Jenny E and Fujii, Sotaro and Moreno-Chicano, Tadeo and Sambongi, Yoshihiro and Svistunenko, Dimitri and Paps, Jordi and Andrew, Colin R and Hough, Michael A (2019) One fold, two functions: cytochrome P460 and cytochrome câ˛-β from the methanotroph Methylococcus capsulatus (Bath). Chemical Science, 10 (10). pp. 3031-3041. DOI https://doi.org/10.1039/c8sc05210g
Horrell, Sam and Kekilli, Demet and Sen, Kakali and Owen, Robin U and Dworkowski, Florian SN and Antonyuk, Svetlana V and Keal, Thomas W and Yong, Chin W and Eady, Robert R and Hasnain, S Samar and Strange, Richard W and Hough, Michael A (2018) Enzyme catalysis captured using multiple structures from one crystal at varying temperatures. IUCrJ, 5 (3). pp. 283-292. DOI https://doi.org/10.1107/S205225251800386X
Straw, Megan L and Chaplin, Amanda K and Hough, Michael A and Paps, Jordi and Bavro, Vassiliy N and Wilson, Michael T and Vijgenboom, Erik and Worrall, Jonathan AR (2018) A cytosolic copper storage protein provides a second level of copper tolerance in Streptomyces lividans. Metallomics: integrated biometal science, 2018 (10). pp. 180-193. DOI https://doi.org/10.1039/c7mt00299h
Sen, Kakali and Horrell, Sam and Kekilli, Demet and Yong, Chin W and Keal, Thomas W and Atakisi, Hakan and Moreau, David W and Thorne, Robert E and Hough, Michael A and Strange, Richard W (2017) Active-site protein dynamics and solvent accessibility in native<i>Achromobacter cycloclastes</i>copper nitrite reductase. IUCrJ, 4 (4). pp. 495-505. DOI https://doi.org/10.1107/s2052252517007527
Hough, Michael A (2017) Choosing the optimal spectroscopic toolkit to understand protein function. Bioscience Reports, 37 (3). BSR20160378-. DOI https://doi.org/10.1042/bsr20160378
Kekilli, Demet and Petersen, Christine A and Pixton, David A and Ghafoor, Dlzar D and Abdullah, Gaylany H and Dworkowski, Florian SN and Wilson, Michael T and Heyes, Derren J and Hardman, Samantha JO and Murphy, Loretta M and Strange, Richard W and Scrutton, Nigel S and Andrew, Colin R and Hough, Michael A (2017) Engineering proximal vs. distal hemeâNO coordination via dinitrosyl dynamics: implications for NO sensor design. Chemical Science, 8 (3). pp. 1986-1994. DOI https://doi.org/10.1039/c6sc04190f
Horrell, Sam and Antonyuk, Svetlana V and Eady, Robert R and Hasnain, S Samar and Hough, Michael A and Strange, Richard W (2016) Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal. IUCrJ, 3 (4). pp. 271-281. DOI https://doi.org/10.1107/s205225251600823x
Chaplin, Amanda K and Wilson, Michael T and Hough, Michael A and Svistunenko, Dimitri A and Hemsworth, Glyn R and Walton, Paul H and Vijgenboom, Erik and Worrall, Jonathan AR (2016) Heterogeneity in the Histidine-brace Copper Coordination Sphere in Auxiliary Activity Family 10 (AA10) Lytic Polysaccharide Monooxygenases. Journal of Biological Chemistry, 291 (24). pp. 12838-12850. DOI https://doi.org/10.1074/jbc.m116.722447
Porto, Tatiana V and Hough, Michael A and Worrall, Jonathan AR (2015) Structural insights into conformational switching in the copper metalloregulator CsoR from<i>Streptomyces lividans</i>. Acta Crystallographica Section D Biological Crystallography, 71 (9). pp. 1872-1878. DOI https://doi.org/10.1107/s1399004715013012
Ghafoor, Dlzar D and Kekilli, Demet and Abdullah, Gaylany H and Dworkowski, Florian SN and Hassan, Hamid G and Wilson, Michael T and Strange, Richard W and Hough, Michael A (2015) Hydrogen bonding of the dissociated histidine ligand is not required for formation of a proximal NO adduct in cytochrome câ. JBIC Journal of Biological Inorganic Chemistry, 20 (6). pp. 949-956. DOI https://doi.org/10.1007/s00775-015-1278-y
Chaplin, Amanda K and Petrus, Marloes LC and Mangiameli, Giulia and Hough, Michael A and Svistunenko, Dimitri A and Nicholls, Peter and Claessen, Dennis and Vijgenboom, Erik and Worrall, Jonathan AR (2015) GlxA is a new structural member of the radical copper oxidase family and is required for glycan deposition at hyphal tips and morphogenesis of <i>Streptomyces lividans</i>. Biochemical Journal, 469 (3). pp. 433-444. DOI https://doi.org/10.1042/bj20150190
Servid, Amy E and McKay, Alison L and Davis, Cherry A and Garton, Elizabeth M and Manole, Andreea and Dobbin, Paul S and Hough, Michael A and Andrew, Colin R (2015) Resonance Raman Spectra of Five-Coordinate Heme-Nitrosyl Cytochromes <i>c</i>â˛: Effect of the Proximal Heme-NO Environment. Biochemistry, 54 (21). pp. 3320-3327. DOI https://doi.org/10.1021/acs.biochem.5b00227
Manole, Andreea and Kekilli, Demet and Svistunenko, Dimitri A and Wilson, Michael T and Dobbin, Paul S and Hough, Michael A (2015) Conformational control of the binding of diatomic gases to cytochrome câ˛. JBIC Journal of Biological Inorganic Chemistry, 20 (4). pp. 675-686. DOI https://doi.org/10.1007/s00775-015-1253-7
Brooke, Greg N and Gamble, Simon C and Hough, Michael A and Begum, Shajna and Dart, D Alwyn and Odontiadis, Michael and Powell, Sue M and Fioretti, Flavia M and Bryan, Rosie A and Waxman, Jonathan and Wait, Robin and Bevan, Charlotte L (2015) Antiandrogens Act as Selective Androgen Receptor Modulators at the Proteome Level in Prostate Cancer Cells*. Molecular & Cellular Proteomics, 14 (5). pp. 1201-1216. DOI https://doi.org/10.1074/mcp.m113.036764
Dworkowski, Florian SN and Hough, Michael A and Pompidor, Guillaume and Fuchs, Martin R (2015) Challenges and solutions for the analysis of<i>in situ</i>,<i>in crystallo</i>micro-spectrophotometric data. Acta Crystallographica Section D Biological Crystallography, 71 (1). pp. 27-35. DOI https://doi.org/10.1107/s1399004714015107
Hough, Michael A and Andrew, Colin R (2015) Cytochromes câ˛. RECENT ADVANCES IN MICROBIAL OXYGEN-BINDING PROTEINS, 67. pp. 1-84. DOI https://doi.org/10.1016/bs.ampbs.2015.08.001
Kekilli, Demet and Dworkowski, Florian SN and Pompidor, Guillaume and Fuchs, Martin R and Andrew, Colin R and Antonyuk, Svetlana and Strange, Richard W and Eady, Robert R and Hasnain, S Samar and Hough, Michael A (2014) Fingerprinting redox and ligand states in haemprotein crystal structures using resonance Raman spectroscopy. Acta Crystallographica Section D Biological Crystallography, 70 (5). pp. 1289-1296. DOI https://doi.org/10.1107/s1399004714004039
Blundell, Katie LIM and Hough, Michael A and Vijgenboom, Erik and Worrall, Jonathan AR (2014) Structural and mechanistic insights into an extracytoplasmic copper trafficking pathway in <i>Streptomyces lividans</i>. Biochemical Journal, 459 (3). pp. 525-538. DOI https://doi.org/10.1042/bj20140017
Barrier, Elise and Braz Fernandes, Francisco Manuel and Bujan, Maya and Feiters, Martin C and Froideval, Annick and Ghijsen, Jacques and Hase, Thomas and Hough, Michael A and Jergel, Matej and Jimenez, Ignacio and Kajander, Tommi and Kikas, Arvo and Kokkinidis, Michael and Kover, Laszlo and Larsen, Helge B and Lawson, David Mark and Lawniczak-Jablonska, Krystyna and Mariani, Carlo and Mikulik, Petr and Monnier, Judith and Morera, Solange and McGuinness, Cormac and MĂźller-Buschbaum, Peter and Meedom Nielson, Martin and Pietsch, Ullrich and Tromp, Moniek and Simon, Marc and Stangl, Julian and Zanotti, Giuseppe (2014) The benefit of the European User Community from transnational access to national radiation facilities. Journal of Synchrotron Radiation, 21 (3). pp. 638-639. DOI https://doi.org/10.1107/s1600577514007619
Reeder, Brandon J and Hough, Michael A (2014) The structure of a class 3 nonsymbiotic plant haemoglobin from<i>Arabidopsis thaliana</i>reveals a novel N-terminal helical extension. Acta Crystallographica Section D Biological Crystallography, 70 (5). pp. 1411-1418. DOI https://doi.org/10.1107/s1399004714004878
Hough, Michael A and Silkstone, Gary and Worrall, JAR and Wilson, Michael T (2014) NO Binding to the Proapoptotic Cytochrome câCardiolipin Complex. NITRIC OXIDE, 96. pp. 193-209. DOI https://doi.org/10.1016/b978-0-12-800254-4.00008-8
Rajagopal, Badri S and Edzuma, Ann N and Hough, Michael A and Blundell, Katie LIM and Kagan, Valerian E and Kapralov, Alexandr A and Fraser, Lewis A and Butt, Julea N and Silkstone, Gary G and Wilson, Michael T and Svistunenko, Dimitri A and Worrall, Jonathan AR (2013) The hydrogen-peroxide-induced radical behaviour in human cytochrome <i>c</i>âphospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant. Biochemical Journal, 456 (3). pp. 441-452. DOI https://doi.org/10.1042/bj20130758
Russell, Henry J and Hardman, Samantha JO and Heyes, Derren J and Hough, Michael A and Greetham, Gregory M and Towrie, Michael and Hay, Sam and Scrutton, Nigel S (2013) Modulation of ligandâheme reactivity by binding pocket residues demonstrated in cytochrome c' over the femtosecondâsecond temporal range. The FEBS Journal, 280 (23). pp. 6070-6082. DOI https://doi.org/10.1111/febs.12526
Strange, Richard W and Hough, Michael A and Antonyuk, Svetlana V and Hasnain, S Samar (2012) Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase. PLoS ONE, 7 (9). e44811-e44811. DOI https://doi.org/10.1371/journal.pone.0044811
Dwarakanath, Srivatsa and Chaplin, Amanda K and Hough, Michael A and Rigali, SĂŠbastien and Vijgenboom, Erik and Worrall, Jonathan AR (2012) Response to Copper Stress in Streptomyces lividans Extends beyond Genes under Direct Control of a Copper-sensitive Operon Repressor Protein (CsoR). Journal of Biological Chemistry, 287 (21). pp. 17833-17847. DOI https://doi.org/10.1074/jbc.m112.352740
Doutch, James and Hough, Michael A and Hasnain, S Samar and Strange, Richard W (2012) Challenges of sulfur SAD phasing as a routine method in macromolecular crystallography. Journal of Synchrotron Radiation, 19 (1). pp. 19-29. DOI https://doi.org/10.1107/s0909049511049004
Antonyuk, Svetlana V and Hough, Michael A (2011) Monitoring and validating active site redox states in protein crystals. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1814 (6). pp. 778-784. DOI https://doi.org/10.1016/j.bbapap.2010.12.017
Leferink, Nicole GH and Han, Cong and Antonyuk, Svetlana V and Heyes, Derren J and Rigby, Stephen EJ and Hough, Michael A and Eady, Robert R and Scrutton, Nigel S and Hasnain, S Samar (2011) Proton-Coupled Electron Transfer in the Catalytic Cycle of <i>Alcaligenes xylosoxidans</i> Copper-Dependent Nitrite Reductase. Biochemistry, 50 (19). pp. 4121-4131. DOI https://doi.org/10.1021/bi200246f
Hough, Michael A and Antonyuk, Svetlana V and Barbieri, Sonia and Rustage, Neil and McKay, Alison L and Servid, Amy E and Eady, Robert R and Andrew, Colin R and Hasnain, S Samar (2011) Distal-to-Proximal NO Conversion in Hemoproteins: The Role of the Proximal Pocket. Journal of Molecular Biology, 405 (2). pp. 395-409. DOI https://doi.org/10.1016/j.jmb.2010.10.035
Brenner, Sibylle and Heyes, Derren J and Hay, Sam and Hough, Michael A and Eady, Robert R and Hasnain, S Samar and Scrutton, Nigel S (2009) Demonstration of Proton-coupled Electron Transfer in the Copper-containing Nitrite Reductases. Journal of Biological Chemistry, 284 (38). pp. 25973-25983. DOI https://doi.org/10.1074/jbc.m109.012245
Hough, Michael A and Eady, Robert R and Hasnain, S Samar (2008) Identification of the Proton Channel to the Active Site Type 2 Cu Center of Nitrite Reductase: Structural and Enzymatic Properties of the His254Phe and Asn90Ser Mutants<sup>,</sup>. Biochemistry, 47 (51). pp. 13547-13553. DOI https://doi.org/10.1021/bi801369y
Ellis, Mark J and Buffey, Steven G and Hough, Michael A and Hasnain, S Samar (2008) On-line optical and X-ray spectroscopies with crystallography: an integrated approach for determining metalloprotein structures in functionally well defined states. Journal of Synchrotron Radiation, 15 (5). pp. 433-439. DOI https://doi.org/10.1107/s0909049508014945
Hough, Michael A and Antonyuk, Svetlana V and Strange, Richard W and Eady, Robert R and Hasnain, S Samar (2008) Crystallography with Online Optical and X-ray Absorption Spectroscopies Demonstrates an Ordered Mechanism in Copper Nitrite Reductase. Journal of Molecular Biology, 378 (2). pp. 353-361. DOI https://doi.org/10.1016/j.jmb.2008.01.097