Items where Author is "Reeves, Philip J"

Article

Reeves, Philip J (2023) Expression systems for bovine rhodopsin: a review of the progress made in the Khorana laboratory. Biophysical Reviews, 15 (1). pp. 93-101. DOI https://doi.org/10.1007/s12551-022-01037-2

Grime, Rachael L and Logan, Richard T and Nestorow, Stephanie A and Sridhar, Pooja and Edwards, Patricia C and Tate, Christopher G and Klumperman, Bert and Dafforn, Tim R and Poyner, David R and Reeves, Philip J and Wheatley, Mark (2021) Differences in SMA-like polymer architecture dictate the conformational changes exhibited by the membrane protein rhodopsin encapsulated in lipid nano-particles. Nanoscale, 13 (31). pp. 13519-13528. DOI https://doi.org/10.1039/d1nr02419a

Sanchez-Reyes, Omar B and Cooke, Aidan LG and Tranter, Dale B and Rashid, Dawood and Eilers, Markus and Reeves, Philip J and Smith, Steven O (2017) G Protein-Coupled Receptors Contain Two Conserved Packing Clusters. Biophysical Journal, 112 (11). pp. 2315-2326. DOI https://doi.org/10.1016/j.bpj.2017.04.051

Athanasiou, Dimitra and Aguila, Monica and Opefi, Chikwado A and South, Kieron and Bellingham, James and Bevilacqua, Dalila and Munro, Peter M and Kanuga, Naheed and Mackenzie, Francesca E and Dubis, Adam M and Georgiadis, Anastasios and Graca, Anna B and Pearson, Rachael A and Ali, Robin R and Sakami, Sanae and Palczewski, Krzysztof and Sherman, Michael Y and Reeves, Philip J and Cheetham, Michael E (2017) Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration. Human Molecular Genetics, 26 (2). pp. 305-319. DOI https://doi.org/10.1093/hmg/ddw387

Kimata, Naoki and Pope, Andreyah and Eilers, Markus and Opefi, Chikwado A and Ziliox, Martine and Hirshfeld, Amiram and Zaitseva, Ekaterina and Vogel, Reiner and Sheves, Mordechai and Reeves, Philip J and Smith, Steven O (2016) Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation. Nature Communications, 7 (1). 12683-. DOI https://doi.org/10.1038/ncomms12683

Kimata, Naoki and Pope, Andreyah and Sanchez-Reyes, Omar B and Eilers, Markus and Opefi, Chikwado A and Ziliox, Martine and Reeves, Philip J and Smith, Steven O (2016) Free backbone carbonyls mediate rhodopsin activation. Nature Structural and Molecular Biology, 23 (8). pp. 738-743. DOI https://doi.org/10.1038/nsmb.3257

Sandoval, Angelica and Eichler, Stefanie and Madathil, Sineej and Reeves, Philip J and Fahmy, Karim and Böckmann, Rainer A (2016) The Molecular Switching Mechanism at the Conserved D(E)RY Motif in Class-A GPCRs. Biophysical Journal, 111 (1). pp. 79-89. DOI https://doi.org/10.1016/j.bpj.2016.06.004

Kimata, Naoki and Reeves, Philip J and Smith, Steven O (2015) Uncovering the triggers for GPCR activation using solid-state NMR spectroscopy. Journal of Magnetic Resonance, 253. pp. 111-118. DOI https://doi.org/10.1016/j.jmr.2014.12.014

Opefi, Chikwado A and Tranter, Dale and Smith, Steven O and Reeves, Philip J (2015) Construction of Stable Mammalian Cell Lines for Inducible Expression of G Protein-Coupled Receptors. MEMBRANE PROTEINS - PRODUCTION AND FUNCTIONAL CHARACTERIZATION, 556. pp. 283-305. DOI https://doi.org/10.1016/bs.mie.2014.12.020

Pope, Andreyah and Eilers, Markus and Reeves, Philip J and Smith, Steven O (2014) Amino acid conservation and interactions in rhodopsin: Probing receptor activation by NMR spectroscopy. Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1837 (5). pp. 683-693. DOI https://doi.org/10.1016/j.bbabio.2013.10.007

Chintapalli, Sree V and Illingworth, Christopher JR and Upton, Graham JG and Sacquin-Mora, Sophie and Reeves, Philip J and Mohammedali, Hani S and Reynolds, Christopher A (2014) Assessing the effect of dynamics on the closed-loop protein-folding hypothesis. Journal of The Royal Society Interface, 11 (91). p. 20130935. DOI https://doi.org/10.1098/rsif.2013.0935

Opefi, Chikwado A and South, Kieron and Reynolds, Christopher A and Smith, Steven O and Reeves, Philip J (2013) Retinitis Pigmentosa Mutants Provide Insight into the Role of the N-terminal Cap in Rhodopsin Folding, Structure, and Function. Journal of Biological Chemistry, 288 (47). pp. 33912-33926. DOI https://doi.org/10.1074/jbc.m113.483032

Vohra, Shabana and Taddese, Bruck and Conner, Alex C and Poyner, David R and Hay, Debbie L and Barwell, James and Reeves, Philip J and Upton, Graham JG and Reynolds, Christopher A (2013) Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies. Journal of The Royal Society Interface, 10 (79). p. 20120846. DOI https://doi.org/10.1098/rsif.2012.0846

Taddese, Bruck and Upton, Graham J G and Bailey, Gregory R and Jordon, Sian R D and Abdalla, Nuradin Y and Reeves, Philip J and Reynolds, Christopher A (2013) Structure and functional motifs of GCR1, the only plant protein with a GPCR fold? Plant Physiology. DOI https://doi.org/10.1104/pp.113.228874

Arakawa, Makoto and Chakraborty, Raja and Upadhyaya, Jasbir and Eilers, Markus and Reeves, Philip J and Smith, Steven O and Chelikani, Prashen (2011) Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β2-adrenergic receptor. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1808 (4). pp. 1170-1178. DOI https://doi.org/10.1016/j.bbamem.2011.01.012

Chintapalli, Sree V and Yew, Boon K and Illingworth, Christopher JR and Upton, Graham JG and Reeves, Philip J and Parkes, Kevin EB and Snell, Christopher R and Reynolds, Christopher A (2010) Closed loop folding units from structural alignments: Experimental foldons revisited. Journal of Computational Chemistry, 31 (15). pp. 2689-2701. DOI https://doi.org/10.1002/jcc.21562

Goncalves, Joseph A and South, Kieron and Ahuja, Shivani and Zaitseva, Ekaterina and Opefi, Chikwado A and Eilers, Markus and Vogel, Reiner and Reeves, Philip J and Smith, Steven O (2010) Highly conserved tyrosine stabilizes the active state of rhodopsin. Proceedings of the National Academy of Sciences, 107 (46). pp. 19861-19866. DOI https://doi.org/10.1073/pnas.1009405107

Hornak, Viktor and Ahuja, Shivani and Eilers, Markus and Goncalves, Joseph A and Sheves, Mordechai and Reeves, Philip J and Smith, Steven O (2010) Light Activation of Rhodopsin: Insights from Molecular Dynamics Simulations Guided by Solid-State NMR Distance Restraints. Journal of Molecular Biology, 396 (3). pp. 510-527. DOI https://doi.org/10.1016/j.jmb.2009.12.003

Ahuja, Shivani and Crocker, Evan and Eilers, Markus and Hornak, Viktor and Hirshfeld, Amiram and Ziliox, Martine and Syrett, Natalie and Reeves, Philip J and Khorana, H Gobind and Sheves, Mordechai and Smith, Steven O (2009) Location of the Retinal Chromophore in the Activated State of Rhodopsin. Journal of Biological Chemistry, 284 (15). pp. 10190-10201. DOI https://doi.org/10.1074/jbc.m805725200

Ahuja, Shivani and Hornak, Viktor and Yan, Elsa CY and Syrett, Natalie and Goncalves, Joseph A and Hirshfeld, Amiram and Ziliox, Martine and Sakmar, Thomas P and Sheves, Mordechai and Reeves, Philip J and Smith, Steven O and Eilers, Markus (2009) Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation. Nature Structural & Molecular Biology, 16 (2). pp. 168-175. DOI https://doi.org/10.1038/nsmb.1549

Takayama, Hidehito and Chelikani, Prashen and Reeves, Philip J and Zhang, Shuguang and Khorana, H Gobind (2008) High-Level Expression, Single-Step Immunoaffinity Purification and Characterization of Human Tetraspanin Membrane Protein CD81. PLoS ONE, 3 (6). e2314-e2314. DOI https://doi.org/10.1371/journal.pone.0002314