Kas, MJH and Fernandes, C and Schalkwyk, LC and Collier, DA (2007) 'Genetics of behavioural domains across the neuropsychiatric spectrum; of mice and men.' Molecular Psychiatry, 12 (4). pp. 324-330. ISSN 1359-4184
Full text not available from this repository.Abstract
Family and twin studies have revealed that genetic factors play a major role in psychiatric disorders, however, attempts to find susceptibility genes for these complex disorders have been largely unsuccessful. Therefore, new research strategies are required to tackle the complex interactions of genes, developmental, and environmental events. Here, we will address a behavioural domain concept that focuses on the genetics of behavioural domains relevant to both animal behaviour and across human psychiatric disorders. We believe that interspecies trait genetics rather than complex syndrome genetics will optimize genotype-phenotype relationships for psychiatric disorders and facilitate the identification of biological substrates underlying these disorders. © 2007 Nature Publishing Group All rights reserved.
Item Type: | Article |
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Uncontrolled Keywords: | psychiatry; animal models; human; endophenotype; behaviour; environment |
Subjects: | Q Science > QH Natural history > QH426 Genetics |
Divisions: | Faculty of Science and Health Faculty of Science and Health > Life Sciences, School of |
SWORD Depositor: | Elements |
Depositing User: | Elements |
Date Deposited: | 17 Dec 2014 19:26 |
Last Modified: | 12 Apr 2022 17:37 |
URI: | http://repository.essex.ac.uk/id/eprint/11042 |
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