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Nucleosome positioning: resources and tools online

Teif, Vladimir B (2016) 'Nucleosome positioning: resources and tools online.' Briefings in Bioinformatics, 17 (5). pp. 745-757. ISSN 1467-5463

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Abstract

Nucleosome positioning is an important process required for proper genome packing and its accessibility to execute the genetic program in a cell-specific, timely manner. In the recent years hundreds of papers have been devoted to the bioinformatics, physics and biology of nucleosome positioning. The purpose of this review is to cover a practical aspect of this field, namely, to provide a guide to the multitude of nucleosome positioning resources available online. These include almost 300 experimental datasets of genome-wide nucleosome occupancy profiles determined in different cell types and more than 40 computational tools for the analysis of experimental nucleosome positioning data and prediction of intrinsic nucleosome formation probabilities from the DNA sequence. A manually curated, up to date list of these resources will be maintained at http://generegulation.info.

Item Type: Article
Additional Information: To appear in Briefings in Bioinformatics
Uncontrolled Keywords: nucleosome positioning; chromatin; DNA-protein binding; MNase-seq; gene regulation; epigenetics
Subjects: Q Science > Q Science (General)
Q Science > QA Mathematics > QA76 Computer software
Q Science > QC Physics
Q Science > QD Chemistry
Divisions: Faculty of Science and Health
Faculty of Science and Health > Life Sciences, School of
SWORD Depositor: Elements
Depositing User: Elements
Date Deposited: 19 Oct 2015 17:01
Last Modified: 18 Jan 2022 11:11
URI: http://repository.essex.ac.uk/id/eprint/15252

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