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The use of Affymetrix GeneChips as a tool for studying alternative forms of RNA

Harrison, Andrew P and Rowsell, Joanna and Camargo, Renata da Silva and Langdon, William B and Stalteri, Maria and Upton, Graham JG and Arteaga-Salas, Jose M (2008) 'The use of Affymetrix GeneChips as a tool for studying alternative forms of RNA.' Biochemical Society Transactions, 36 (3). pp. 511-513. ISSN 0300-5127

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Abstract

<jats:p>We are developing a computational pipeline to use surveys of Affymetrix GeneChips as a discovery tool for unravelling some of the biology associated with post-transcriptional processing of RNA. This work involves the integration of a number of bioinformatics resources, from comparing annotations to processing images to determining the structure of transcripts. The rapidly growing datasets of GeneChips available to the community puts us in a strong position to discover novel biology about post-transcriptional processing, and should enable us to determine the mechanisms by which some groups of genes make co-ordinated changes in their production of isoforms.</jats:p>

Item Type: Article
Uncontrolled Keywords: Animals; Humans; RNA; Oligonucleotide Array Sequence Analysis; Polyadenylation; Alternative Splicing
Subjects: Q Science > QA Mathematics
Q Science > QH Natural history > QH301 Biology
Q Science > QH Natural history > QH426 Genetics
Divisions: Faculty of Science and Health
Faculty of Science and Health > Mathematical Sciences, Department of
SWORD Depositor: Elements
Depositing User: Elements
Date Deposited: 30 Sep 2011 10:26
Last Modified: 15 Jan 2022 00:45
URI: http://repository.essex.ac.uk/id/eprint/832

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