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Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer

Chrysostomou, Stelios and Roy, Rajat and Prischi, Filippo and Thamlikitkul, Lucksamon and Chapman, Kathryn L and Mufti, Uwais and Peach, Robert and Ding, Laifeng and Hancock, David and Moore, Christopher and Molina-Arcas, Miriam and Mauri, Francesco and Pinato, David J and Abrahams, Joel M and Ottaviani, Silvia and Castellano, Leandro and Giamas, Georgios and Pascoe, Jennifer and Moonamale, Devmini and Pirrie, Sarah and Gaunt, Claire and Billingham, Lucinda and Steven, Neil M and Cullen, Michael and Hrouda, David and Winkler, Mathias and Post, John and Cohen, Philip and Salpeter, Seth J and Bar, Vered and Zundelevich, Adi and Golan, Shay and Leibovici, Dan and Lara, Romain and Klug, David R and Yaliraki, Sophia N and Barahona, Mauricio and Wang, Yulan and Downward, Julian and Skehel, J Mark and Ali, Maruf MU and Seckl, Michael J and Pardo, Olivier E (2021) Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer. Science Translational Medicine, 13 (602). eaba4627-. DOI https://doi.org/10.1126/scitranslmed.aba4627



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