Mason, Maria G and Shepherd, Mark and Nicholls, Peter and Dobbin, Paul S and Dodsworth, Kathryn S and Poole, Robert K and Cooper, Chris E (2009) Cytochrome bd confers nitric oxide resistance to Escherichia coli. Nature Chemical Biology, 5 (2). pp. 94-96. DOI https://doi.org/10.1038/nchembio.135
Mason, Maria G and Shepherd, Mark and Nicholls, Peter and Dobbin, Paul S and Dodsworth, Kathryn S and Poole, Robert K and Cooper, Chris E (2009) Cytochrome bd confers nitric oxide resistance to Escherichia coli. Nature Chemical Biology, 5 (2). pp. 94-96. DOI https://doi.org/10.1038/nchembio.135
Mason, Maria G and Shepherd, Mark and Nicholls, Peter and Dobbin, Paul S and Dodsworth, Kathryn S and Poole, Robert K and Cooper, Chris E (2009) Cytochrome bd confers nitric oxide resistance to Escherichia coli. Nature Chemical Biology, 5 (2). pp. 94-96. DOI https://doi.org/10.1038/nchembio.135
Abstract
The aerobic respiratory chain of Escherichia coli has two terminal quinol oxidases: cytochrome bo and cytochrome bd. Cytochrome bd was thought to function solely to facilitate micro-aerobic respiration. However, it has recently been shown to be overexpressed under conditions of nitric oxide (NO) stress; we show here that cytochrome bd is crucial for protecting E. coli cells from NO-induced growth inhibition by virtue of its fast NO dissociation rate. © 2009 Nature America, Inc. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Escherichia coli; Nitric Oxide; Cytochromes; Cytochrome b Group; Electron Transport Chain Complex Proteins; Oxidoreductases; Escherichia coli Proteins |
| Subjects: | Q Science > QH Natural history > QH301 Biology |
| Divisions: | Faculty of Science and Health Faculty of Science and Health > Life Sciences, School of |
| SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
| Depositing User: | Unnamed user with email elements@essex.ac.uk |
| Date Deposited: | 15 Sep 2011 12:32 |
| Last Modified: | 04 Dec 2024 06:11 |
| URI: | http://repository.essex.ac.uk/id/eprint/745 |