Rod, Naja Hulvej and Kumari, Meena and Lange, Theis and Kivimäki, Mika and Shipley, Martin and Ferrie, Jane (2014) The Joint Effect of Sleep Duration and Disturbed Sleep on Cause-Specific Mortality: Results from the Whitehall II Cohort Study. PLoS ONE, 9 (4). e91965-e91965. DOI https://doi.org/10.1371/journal.pone.0091965
Rod, Naja Hulvej and Kumari, Meena and Lange, Theis and Kivimäki, Mika and Shipley, Martin and Ferrie, Jane (2014) The Joint Effect of Sleep Duration and Disturbed Sleep on Cause-Specific Mortality: Results from the Whitehall II Cohort Study. PLoS ONE, 9 (4). e91965-e91965. DOI https://doi.org/10.1371/journal.pone.0091965
Rod, Naja Hulvej and Kumari, Meena and Lange, Theis and Kivimäki, Mika and Shipley, Martin and Ferrie, Jane (2014) The Joint Effect of Sleep Duration and Disturbed Sleep on Cause-Specific Mortality: Results from the Whitehall II Cohort Study. PLoS ONE, 9 (4). e91965-e91965. DOI https://doi.org/10.1371/journal.pone.0091965
Abstract
Background: Both sleep duration and sleep quality are related to future health, but their combined effects on mortality are unsettled. We aimed to examine the individual and joint effects of sleep duration and sleep disturbances on cause-specific mortality in a large prospective cohort study. Methods: We included 9,098 men and women free of pre-existing disease from the Whitehall II study, UK. Sleep measures were self-reported at baseline (1985-1988). Participants were followed until 2010 in a nationwide death register for total and cause-specific (cardiovascular disease, cancer and other) mortality. Results: There were 804 deaths over a mean 22 year follow-up period. In men, short sleep (≤6 hrs/night) and disturbed sleep were not independently associated with CVD mortality, but there was an indication of higher risk among men who experienced both (HR = 1.57; 95% CI: 0.96-2.58). In women, short sleep and disturbed sleep were independently associated with CVD mortality, and women with both short and disturbed sleep experienced a much higher risk of CVD mortality (3.19; 1.52-6.72) compared to those who slept 7-8 hours with no sleep disturbances; equivalent to approximately 90 additional deaths per 100,000 person years. Sleep was not associated with death due to cancer or other causes. Conclusion: Both short sleep and disturbed sleep are independent risk factors for CVD mortality in women and future studies on sleep may benefit from assessing disturbed sleep in addition to sleep duration in order to capture health-relevant features of inadequate sleep. © 2014 Rod et al.
Item Type: | Article |
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Uncontrolled Keywords: | Humans; Neoplasms; Sleep Deprivation; Cardiovascular Diseases; Prognosis; Survival Rate; Cohort Studies; Follow-Up Studies; Time Factors; Adult; Middle Aged; Female; Male |
Subjects: | H Social Sciences > H Social Sciences (General) R Medicine > R Medicine (General) |
Divisions: | Faculty of Social Sciences Faculty of Social Sciences > Institute for Social and Economic Research |
SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
Depositing User: | Unnamed user with email elements@essex.ac.uk |
Date Deposited: | 29 Sep 2015 12:18 |
Last Modified: | 30 Oct 2024 16:08 |
URI: | http://repository.essex.ac.uk/id/eprint/15173 |
Available files
Filename: journal.pone.0091965.pdf
Licence: Creative Commons: Attribution 3.0