Teif, Vladimir B (2016) Nucleosome positioning: resources and tools online. Briefings in Bioinformatics, 17 (5). pp. 745-757. DOI https://doi.org/10.1093/bib/bbv086
Teif, Vladimir B (2016) Nucleosome positioning: resources and tools online. Briefings in Bioinformatics, 17 (5). pp. 745-757. DOI https://doi.org/10.1093/bib/bbv086
Teif, Vladimir B (2016) Nucleosome positioning: resources and tools online. Briefings in Bioinformatics, 17 (5). pp. 745-757. DOI https://doi.org/10.1093/bib/bbv086
Abstract
Nucleosome positioning is an important process required for proper genome packing and its accessibility to execute the genetic program in a cell-specific, timely manner. In the recent years hundreds of papers have been devoted to the bioinformatics, physics and biology of nucleosome positioning. The purpose of this review is to cover a practical aspect of this field, namely, to provide a guide to the multitude of nucleosome positioning resources available online. These include almost 300 experimental datasets of genome-wide nucleosome occupancy profiles determined in different cell types and more than 40 computational tools for the analysis of experimental nucleosome positioning data and prediction of intrinsic nucleosome formation probabilities from the DNA sequence. A manually curated, up to date list of these resources will be maintained at http://generegulation.info.
Item Type: | Article |
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Additional Information: | To appear in Briefings in Bioinformatics |
Uncontrolled Keywords: | nucleosome positioning; chromatin; DNA-protein binding; MNase-seq; gene regulation; epigenetics |
Subjects: | Q Science > Q Science (General) Q Science > QA Mathematics > QA76 Computer software Q Science > QC Physics Q Science > QD Chemistry |
Divisions: | Faculty of Science and Health Faculty of Science and Health > Life Sciences, School of |
SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
Depositing User: | Unnamed user with email elements@essex.ac.uk |
Date Deposited: | 19 Oct 2015 17:01 |
Last Modified: | 07 Aug 2024 20:08 |
URI: | http://repository.essex.ac.uk/id/eprint/15252 |
Available files
Filename: _Teif2015_nucleosome_positioning_online_v44.pdf