B. Teif, Vladimir and G. Cherstvy, Andrey (2016) Chromatin and epigenetics: current biophysical views. AIMS Biophysics, 3 (1). pp. 88-98. DOI https://doi.org/10.3934/biophy.2016.1.88
B. Teif, Vladimir and G. Cherstvy, Andrey (2016) Chromatin and epigenetics: current biophysical views. AIMS Biophysics, 3 (1). pp. 88-98. DOI https://doi.org/10.3934/biophy.2016.1.88
B. Teif, Vladimir and G. Cherstvy, Andrey (2016) Chromatin and epigenetics: current biophysical views. AIMS Biophysics, 3 (1). pp. 88-98. DOI https://doi.org/10.3934/biophy.2016.1.88
Abstract
Recent advances in high-throughput sequencing experiments and their theoretical descriptions have determined fast dynamics of the "chromatin and epigenetics" field, with new concepts appearing at high rate. This field includes but is not limited to the study of DNA-protein-RNA interactions, chromatin packing properties at different scales, regulation of gene expression and protein trafficking in the cell nucleus, binding site search in the crowded chromatin environment and modulation of physical interactions by covalent chemical modifications of the binding partners. The current special issue does not pretend for the full coverage of the field, but it rather aims to capture its development and provide a snapshot of the most recent concepts and approaches. Eighteen open-access articles comprising this issue provide a delicate balance between current theoretical and experimental biophysical approaches to uncover chromatin structure and understand epigenetic regulation, allowing free flow of new ideas and preliminary results.
Item Type: | Article |
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Uncontrolled Keywords: | chromatin; epigenetics; linker histones; nucleosome; DNA-protein binding; histone modifications; remodelers; topologically associated domains; DNA methylation; DNA supercoiling |
Subjects: | Q Science > QA Mathematics Q Science > QC Physics Q Science > QH Natural history > QH301 Biology Q Science > QH Natural history > QH426 Genetics |
Divisions: | Faculty of Science and Health Faculty of Science and Health > Life Sciences, School of |
SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
Depositing User: | Unnamed user with email elements@essex.ac.uk |
Date Deposited: | 08 Mar 2016 11:38 |
Last Modified: | 07 Aug 2024 16:44 |
URI: | http://repository.essex.ac.uk/id/eprint/16223 |
Available files
Filename: biophys-03-00088.pdf
Licence: Creative Commons: Attribution 3.0