Benarous, Leila and Benarous, Khedidja and Muhammad, Ghulam and Ali, Zulfiqar (2022) Deep learning application detecting SARS-CoV-2 key enzymes inhibitors. Cluster Computing, 26 (2). pp. 1169-1180. DOI https://doi.org/10.1007/s10586-022-03656-6
Benarous, Leila and Benarous, Khedidja and Muhammad, Ghulam and Ali, Zulfiqar (2022) Deep learning application detecting SARS-CoV-2 key enzymes inhibitors. Cluster Computing, 26 (2). pp. 1169-1180. DOI https://doi.org/10.1007/s10586-022-03656-6
Benarous, Leila and Benarous, Khedidja and Muhammad, Ghulam and Ali, Zulfiqar (2022) Deep learning application detecting SARS-CoV-2 key enzymes inhibitors. Cluster Computing, 26 (2). pp. 1169-1180. DOI https://doi.org/10.1007/s10586-022-03656-6
Abstract
The fast spread of the COVID-19 over the world pressured scientists to find its cures. Especially, with the disastrous results, it engendered from human life losses to long-term impacts on infected people's health and the huge financial losses. In addition to the massive efforts made by researchers and medicals on finding safe, smart, fast, and efficient methods to accurately make an early diagnosis of the COVID-19. Some researchers focused on finding drugs to treat the disease and its symptoms, others worked on creating effective vaccines, while several concentrated on finding inhibitors for the key enzymes of the virus, to reduce its spreading and reproduction inside the human body. These enzymes' inhibitors are usually found in aliments, plants, fungi, or even in some drugs. Since these inhibitors slow and halt the replication of the virus in the human body, they can help fight it at an early stage saving the patient from death risk. Moreover, if the human body's immune system gets rid of the virus at the early stage it can be spared from the disastrous sequels it may leave inside the patient's body. Our research aims to find aliments and plants that are rich in these inhibitors. In this paper, we developed a deep learning application that is trained with various aliments, plants, and drugs to detect if a component contains SARS-CoV-2 key inhibitor(s) intending to help them find more sources containing these inhibitors. The application is trained to identify various sources rich in thirteen coronavirus-2 key inhibitors. The sources are currently just aliments, plants, and seeds and the identification is done by their names.
Item Type: | Article |
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Uncontrolled Keywords: | Key enzymes inhibitors; COVID-19; Deep learning; Plants; Aliments; Identification |
Divisions: | Faculty of Science and Health Faculty of Science and Health > Computer Science and Electronic Engineering, School of |
SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
Depositing User: | Unnamed user with email elements@essex.ac.uk |
Date Deposited: | 10 Feb 2023 17:20 |
Last Modified: | 30 Oct 2024 20:48 |
URI: | http://repository.essex.ac.uk/id/eprint/33481 |
Available files
Filename: accepted Manuscript.pdf