Upton, GJG and Sanchez-Graillet, O and Rowsell, J and Arteaga-Salas, JM and Graham, NS and Stalteri, MA and Memon, FN and May, ST and Harrison, AP (2009) On the causes of outliers in Affymetrix GeneChip data. Briefings in Functional Genomics and Proteomics, 8 (3). pp. 199-212. DOI https://doi.org/10.1093/bfgp/elp027
Upton, GJG and Sanchez-Graillet, O and Rowsell, J and Arteaga-Salas, JM and Graham, NS and Stalteri, MA and Memon, FN and May, ST and Harrison, AP (2009) On the causes of outliers in Affymetrix GeneChip data. Briefings in Functional Genomics and Proteomics, 8 (3). pp. 199-212. DOI https://doi.org/10.1093/bfgp/elp027
Upton, GJG and Sanchez-Graillet, O and Rowsell, J and Arteaga-Salas, JM and Graham, NS and Stalteri, MA and Memon, FN and May, ST and Harrison, AP (2009) On the causes of outliers in Affymetrix GeneChip data. Briefings in Functional Genomics and Proteomics, 8 (3). pp. 199-212. DOI https://doi.org/10.1093/bfgp/elp027
Abstract
We describe various types of outliers seen in Affymetrix GeneChip data. We have been able to utilise the data in the Gene Expression Omnibus to screen GeneChips across a range of scales, from single probes, to spatially adjacent fractions of arrays, to whole arrays, to whole experiments. In this review we describe a number of causes for why some reported intensities might be misleading on GeneChips. © The Author 2009. Published by Oxford University Press.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Humans; DNA Probes; Artifacts; Oligonucleotide Array Sequence Analysis; Base Sequence; Molecular Sequence Data; Statistics as Topic |
| Subjects: | Q Science > QA Mathematics Q Science > QH Natural history > QH426 Genetics |
| Divisions: | Faculty of Science and Health Faculty of Science and Health > Mathematics, Statistics and Actuarial Science, School of |
| SWORD Depositor: | Unnamed user with email elements@essex.ac.uk |
| Depositing User: | Unnamed user with email elements@essex.ac.uk |
| Date Deposited: | 06 Sep 2011 14:01 |
| Last Modified: | 23 Oct 2024 06:20 |
| URI: | http://repository.essex.ac.uk/id/eprint/61 |