Items where Author is "Poyner, David R"

Grime, Rachael L and Logan, Richard T and Nestorow, Stephanie A and Sridhar, Pooja and Edwards, Patricia C and Tate, Christopher G and Klumperman, Bert and Dafforn, Tim R and Poyner, David R and Reeves, Philip J and Wheatley, Mark (2021) Differences in SMA-like polymer architecture dictate the conformational changes exhibited by the membrane protein rhodopsin encapsulated in lipid nano-particles. Nanoscale, 13 (31). pp. 13519-13528. DOI https://doi.org/10.1039/d1nr02419a

Simms, John and Uddin, Romez and Sakmar, Thomas P and Gingell, Joseph J and Garelja, Michael L and Hay, Debbie L and Brimble, Margaret A and Harris, Paul WR and Reynolds, Christopher A and Poyner, David R (2018) Photoaffinity cross-linking and unnatural amino acid mutagenesis reveal insights into calcitonin gene-related peptide binding to the calcitonin receptor-like receptor/receptor activity-modifying protein 1 (CLR/RAMP1) complex. Biochemistry, 57 (32). pp. 4915-4922. DOI https://doi.org/10.1021/acs.biochem.8b00502

Woolley, Michael J and Reynolds, Christopher A and Simms, John and Walker, Christopher S and Mobarec, Juan Carlos and Garelja, Michael L and Conner, Alex C and Poyner, David R and Hay, Debbie L (2017) Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs. Biochemical Pharmacology, 142. pp. 96-110. DOI https://doi.org/10.1016/j.bcp.2017.07.005

Woolley, Michael J and Simms, John and Mobarec, Juan Carlos and Reynolds, Christopher A and Poyner, David R and Conner, Alex C (2017) Understanding the molecular functions of the second extracellular loop (ECL2) of the calcitonin gene-related peptide (CGRP) receptor using a comprehensive mutagenesis approach. Molecular and Cellular Endocrinology, 454 (C). pp. 39-49. DOI https://doi.org/10.1016/j.mce.2017.05.034

Weston, Cathryn and Winfield, Ian and Harris, Matthew and Hodgson, Rose and Shah, Archna and Dowell, Simon J and Mobarec, Juan Carlos and Woodlock, David A and Reynolds, Christopher A and Poyner, David R and Watkins, Harriet A and Ladds, Graham (2016) Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors. Journal of Biological Chemistry, 291 (42). pp. 21925-21944. DOI https://doi.org/10.1074/jbc.M116.751362

Watkins, Harriet A and Chakravarthy, Madhuri and Abhayawardana, Rekhati S and Gingell, Joseph J and Garelja, Michael and Pardamwar, Meenakshi and McElhinney, James MWR and Lathbridge, Alex and Constantine, Arran and Harris, Paul WR and Yuen, Tsz-Ying and Brimble, Margaret A and Barwell, James and Poyner, David R and Woolley, Michael J and Conner, Alex C and Pioszak, Augen A and Reynolds, Christopher A and Hay, Debbie L (2016) Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties. Journal of Biological Chemistry, 291 (22). pp. 11657-11675. DOI https://doi.org/10.1074/jbc.m115.688218

Hay, Debbie L and Walker, Christopher S and Gingell, Joseph J and Ladds, Graham and Reynolds, Christopher A and Poyner, David R (2016) Receptor activity-modifying proteins; multifunctional G protein-coupled receptor accessory proteins. Biochemical Society Transactions, 44 (2). pp. 568-573. DOI https://doi.org/10.1042/BST20150237

Woolley, Michael J and Watkins, Harriet A and Taddese, Bruck and Karakullukcu, Z Gamze and Barwell, James and Smith, Kevin J and Hay, Debbie L and Poyner, David R and Reynolds, Christopher A and Conner, Alex C (2013) The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach. Journal of The Royal Society Interface, 10 (88). p. 20130589. DOI https://doi.org/10.1098/rsif.2013.0589

Vohra, Shabana and Taddese, Bruck and Conner, Alex C and Poyner, David R and Hay, Debbie L and Barwell, James and Reeves, Philip J and Upton, Graham JG and Reynolds, Christopher A (2013) Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies. Journal of The Royal Society Interface, 10 (79). p. 20120846. DOI https://doi.org/10.1098/rsif.2012.0846

Barwell, James and Wheatley, Mark and Conner, Alex C and Taddese, Bruck and Vohra, Shabana and Reynolds, Christopher A and Poyner, David R (2013) The activation of the CGRP receptor. Biochemical Society Transactions, 41 (1). pp. 180-184. DOI https://doi.org/10.1042/bst20120251