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Lucic, Marina and Chaplin, Amanda K and Moreno-Chicano, Tadeo and Dworkowski, Florian and Wilson, Michael and Svistunenko, Dimitri and Hough, Michael and Worrall, Jonathan AR (2020) A subtle structural change in the distal haem pocket has a remarkable effect on tuning hydrogen peroxide reactivity in dye decolourising peroxidases from Streptomyces lividans. Dalton Transactions, 49 (5). pp. 1620-1636. DOI https://doi.org/10.1039/c9dt04583j
Ebrahim, Ali and Moreno-Chicano, Tadeo and Appleby, Martin V and Chaplin, Amanda K and Beale, John H and Sherrell, Darren A and Duyvesteyn, Helen ME and Owada, Shigeki and Tono, Kensuke and Sugimoto, Hiroshi and Strange, Richard W and Worrall, Jonathan AR and Axford, Danny and Owen, Robin L and Hough, Michael A (2019) Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins. IUCrJ, 6 (4). pp. 543-551. DOI https://doi.org/10.1107/s2052252519003956
Chaplin, Amanda K and Chicano, Tadeo Moreno and Hampshire, Bethany V and Wilson, Michael T and Hough, Michael A and Svistunenko, Dimitri A and Worrall, Jonathan AR (2019) An Aromatic Dyad Motif in Dye Decolourising Peroxidases Has Implications for Free Radical Formation and Catalysis. Chemistry â A European Journal, 25 (24). pp. 6141-6153. DOI https://doi.org/10.1002/chem.201806290
Chaplin, Amanda K and Chernukhin, Igor and Bechtold, Ulrike (2019) Profiling of advanced glycation end products uncovers abiotic stress-specific target proteins in Arabidopsis. Journal of Experimental Botany, 70 (2). pp. 653-670. DOI https://doi.org/10.1093/jxb/ery389
Straw, Megan L and Chaplin, Amanda K and Hough, Michael A and Paps, Jordi and Bavro, Vassiliy N and Wilson, Michael T and Vijgenboom, Erik and Worrall, Jonathan AR (2018) A cytosolic copper storage protein provides a second level of copper tolerance in Streptomyces lividans. Metallomics: integrated biometal science, 2018 (10). pp. 180-193. DOI https://doi.org/10.1039/c7mt00299h
Chaplin, AK and Wilson, MT and Worrall, JAR (2017) Kinetic characterisation of a dye decolourising peroxidase from Streptomyces lividans: New insight into the mechanism of anthraquinone dye decolourisation. Dalton Transactions, 46 (29). pp. 9420-9429. DOI https://doi.org/10.1039/c7dt01144j
Chaplin, AK and Bernini, C and Sinicropi, A and Basosi, R and Worrall, JAR and Svistunenko, DA (2017) Tyrosine or Tryptophan? Modifying a Metalloradical Catalytic Site by Removal of the CysâTyr CrossâLink in the Galactose 6âOxidase Homologue GlxA. Angewandte Chemie International Edition, 129 (23). pp. 6602-6606. DOI https://doi.org/10.1002/ange.201701270
Kekilli, D and Moreno-Chicano, T and Chaplin, AK and Horrell, S and Dworkowski, FSN and Worrall, JAR and Strange, RW and Hough, MA (2017) Photoreduction and validation of haem?ligand intermediate states in protein crystals by in situ single-crystal spectroscopy and diffraction. IUCrJ, 4 (3). pp. 263-270. DOI https://doi.org/10.1107/S2052252517002159
Chaplin, AK and Svistunenko, DA and Hough, MA and Wilson, MT and Vijgenboom, E and Worrall, JAR (2017) Active site maturation and activity of the copper-radical oxidase GlxA is governed by a tryptophan residue. The Biochemical Journal, 474 (5). pp. 809-825. DOI https://doi.org/10.1042/BCJ20160968
Chaplin, Amanda K and Wilson, Michael T and Hough, Michael A and Svistunenko, Dimitri A and Hemsworth, Glyn R and Walton, Paul H and Vijgenboom, Erik and Worrall, Jonathan AR (2016) Heterogeneity in the Histidine-brace Copper Coordination Sphere in Auxiliary Activity Family 10 (AA10) Lytic Polysaccharide Monooxygenases. Journal of Biological Chemistry, 291 (24). pp. 12838-12850. DOI https://doi.org/10.1074/jbc.m116.722447
Petrus, Marloes LC and Vijgenboom, Erik and Chaplin, Amanda K and Worrall, Jonathan AR and van Wezel, Gilles P and Claessen, Dennis (2016) The DyP-type peroxidase DtpA is a Tat-substrate required for GlxA maturation and morphogenesis in <i>Streptomyces</i>. Open Biology, 6 (1). p. 150149. DOI https://doi.org/10.1098/rsob.150149
Chaplin, Amanda K and Petrus, Marloes LC and Mangiameli, Giulia and Hough, Michael A and Svistunenko, Dimitri A and Nicholls, Peter and Claessen, Dennis and Vijgenboom, Erik and Worrall, Jonathan AR (2015) GlxA is a new structural member of the radical copper oxidase family and is required for glycan deposition at hyphal tips and morphogenesis of <i>Streptomyces lividans</i>. Biochemical Journal, 469 (3). pp. 433-444. DOI https://doi.org/10.1042/bj20150190
Chaplin, Amanda K and Tan, Benedict G and Vijgenboom, Erik and Worrall, Jonathan AR (2015) Copper trafficking in the CsoR regulon of Streptomyces lividans. Metallomics, 7 (1). pp. 145-155. DOI https://doi.org/10.1039/c4mt00250d
Dwarakanath, Srivatsa and Chaplin, Amanda K and Hough, Michael A and Rigali, Sébastien and Vijgenboom, Erik and Worrall, Jonathan AR (2012) Response to Copper Stress in Streptomyces lividans Extends beyond Genes under Direct Control of a Copper-sensitive Operon Repressor Protein (CsoR). Journal of Biological Chemistry, 287 (21). pp. 17833-17847. DOI https://doi.org/10.1074/jbc.m112.352740
Thesis
Chaplin, Amanda K (2016) Metalloenzymes required for glycan processing and morphological development in Streptomyces lividans. PhD thesis, University of Essex.