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PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

Schmidt, AF and Swerdlow, DI and Holmes, MV and Patel, RS and Fairhurst-Hunter, Z and Lyall, DM and Hartwig, FP and Horta, BL and Hyppönen, E and Power, C and Moldovan, M and van Iperen, E and Hovingh, GK and Demuth, I and Norman, K and Steinhagen-Thiessen, E and Demuth, J and Bertram, L and Liu, T and Coassin, S and Willeit, J and Kiechl, S and Willeit, K and Mason, D and Wright, J and Morris, R and Wanamethee, G and Whincup, P and Ben-Shlomo, Y and McLachlan, S and Price, JF and Kivimaki, M and Welch, C and Sanchez-Galvez, A and Marques-Vidal, P and Nicolaides, A and Panayiotou, AG and Onland-Moret, NC and van der Schouw, YT and Matullo, G and Fiorito, G and Guarrera, S and Sacerdote, C and Wareham, NJ and Langenberg, C and Scott, R and Luan, J and Bobak, M and Malyutina, S and Pająk, A and Kubinova, R and Tamosiunas, A and Pikhart, H and Husemoen, LLN and Grarup, N and Pedersen, O and Hansen, T and Linneberg, A and Simonsen, KS and Cooper, J and Humphries, SE and Brilliant, M and Kitchner, T and Hakonarson, H and Carrell, DS and McCarty, CA and Kirchner, HL and Larson, EB and Crosslin, DR and de Andrade, M and Roden, DM and Denny, JC and Carty, C and Hancock, S and Attia, J and Holliday, E and O'Donnell, M and Yusuf, S and Chong, M and Pare, G and van der Harst, P and Said, MA and Eppinga, RN and Verweij, N and Snieder, H and Christen, T and Mook-Kanamori, DO and Gustafsson, S and Lind, L and Ingelsson, E and Pazoki, R and Franco, O and Hofman, A and Uitterlinden, A and Dehghan, A and Teumer, A and Baumeister, S and Dörr, M and Lerch, MM and Völker, U and Völzke, H and Ward, J and Pell, JP and Smith, DJ and Meade, T and Maitland-van der Zee, AH and Baranova, EV and Young, R and Ford, I and Campbell, A and Padmanabhan, S and Bots, ML and Grobbee, DE and Froguel, P and Thuillier, D and Balkau, B and Bonnefond, A and Cariou, B and Smart, M and Bao, Y and Kumari, M and Mahajan, A and Ridker, PM and Chasman, DI and Reiner, AP and Lange, LA and Ritchie, MD and Asselbergs, FW and Casas, J-P and Keating, BJ and Preiss, D and Hingorani, AD and Sattar, N (2017) PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study. The Lancet Diabetes and Endocrinology, 5 (2). pp. 97-105. DOI https://doi.org/10.1016/S2213-8587(16)30396-5



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